Medicinal fungi have a long history of use nutritional, medicinal and pharmacological properties. Their extracts, such as polysaccharide, protein etc, are widely sold as nutritional supplements and touted as beneficial for health, due to their medicinal effects, possibly including hepato-protection, antitumor, immuno-modulation. The work in this dissertation was based on submerged fermentation of Agaricus blazei Murill、 Ganoderma lucidum and Grifola frondosa to enrich the trace element in order to select a ...