【作者】 袁峰； 陈虹羽； 丁勇成； 王颖； 廖启杭； 王腾； 樊秦亚； 冯子岳； 张楚楚； 傅光翮； 邹欣庆；

【Author】 Feng Yuan;Hongyu Chen;Yongcheng Ding;Ying Wang;Qihang Liao;Teng Wang;Qinya Fan;Ziyue Feng;Chuchu Zhang;Guanghe Fu;Xinqing Zou;Nanjing University, School of Geographic and Oceanographic Sciences;Nanjing University, Ministry of Education Key Laboratory for Coast and Island Development;Nanjing University, Collaborative Innovation Center of South China Sea Studies;Hohai University, College of Oceanography;

【机构】 南京大学地理与海洋科学学院； 南京大学海岸与海岛开发教育部重点实验室； 南京大学中国南海研究协同创新中心； 河海大学海洋学院；

【摘要】 水生生态系统是环境中微塑料(MPs)的主要归宿地之一。进入水生生态系统的MPs可与其他共存污染物一起造成复合污染。然而,与共存污染物单独造成的毒性相比,复合污染对鱼类的毒性是更高还是更低,仍有争议性。本研究旨在缩小这一研究空白,基于从55个实验室研究中收集的环境MP浓度背景下的1380个生物学终点。总的来说,共存污染物溶液中的MPs显著增加了对鱼类的毒性。具体来说,MPs增加了对免疫系统、新陈代谢和氧化损伤的负面影响。亚组分析表明,毒性的变化与鱼的生长阶段和MP大小有关,但与共存污染物类型和MP类型无关。荟萃回归分析表明,毒性的变化与辛醇-水分配系数的对数(logKow)以及暴露时间无关。最后,从四个方面讨论了实验室研究和实际水生环境之间的差异:MPs、共存污染物、环境因素和实验对象。我们的研究为从复合污染角度进一步了解MPs对水生生物的潜在影响提供了基础。此外,我们的研究结果可以为水生生态系统的保护和管理提供参考。更多还原

【Abstract】 Aquatic ecosystems are among the main destination for microplastics(MPs) in the environment. MPs that enter aquatic ecosystems can contribute to pollution together with other co-existing pollutants. However, whether such pollution results in higher or lower toxicity to fish than that caused by co-existing pollutants alone remains controversial. This study aimed at closing this research gap based on 1380 biological endpoints under the background of environmental MP concentrations collected from 55 laboratory studies. Overall, MPs in co-existing pollutant solutions significantly increased the toxicity to fish. Specifically, MPs elevated negative effects on the immune system, metabolism, and oxidative damage. Subgroup analysis indicated that changes in toxicity were related to fish life stage and MP size, but not to co-existing pollutant or MP type.Meta-regression analysis indicated that changes in toxicity were not related to the logarithm of the octanol-water partition coefficient(logKow) or exposure time. Finally, the differences between laboratory research and the actual aquatic environment were discussed from four aspects: MPs,co-existing pollutants, environmental factors, and experimental objects. Our study provides a basis for further understanding the potential impact of MPs on aquatic organisms from a combined pollution perspective. Moreover, our results can provide a reference for the conservation and management of aquatic ecosystems.更多还原