Formation of disinfection by-products during chlorination of organic matter from phoenix tree leaves and Chlorella vulgaris

【作者】 董文琪； 孙洪杰； 张瑜； 林红军； 陈建荣； 洪华嫦；

【机构】 浙江师范大学地理与环境科学学院；

【摘要】 Low concentrations of arsenic(As) contamination in aquatic environment is a worldwide issue, which is of great concern. To evaluate the impact of low concentrations of As on zebrafish, we measured the growth, antioxidant enzymes including superoxide dismutase(SOD) and catalase(CAT), oxidative damage(malondialdehyde, MDA) and apoptosis-related genes(nrf2, p53 and c-jun) of adult zebrafish after exposing to different AsⅢ concentrations(0, 10, 50, 100 or 150 μg L-1)for 28 d. Results indicated that exposure to low AsⅢ concentrations decreased the zebrafish weight by 14%, increased the activities of SOD and CAT by 23-41% and31-59%, decreased the contents of MDA by 29-54%, and modulated transcription of apoptosis related genes. Our study showed that chronic exposure to AsⅢ concentrations < 150 μg L-1 generated oxidative stress and damage on zebrafish, and altered apoptosis-related genes in zebrafish.更多还原

【Abstract】 Low concentrations of arsenic(As) contamination in aquatic environment is a worldwide issue, which is of great concern. To evaluate the impact of low concentrations of As on zebrafish, we measured the growth, antioxidant enzymes including superoxide dismutase(SOD) and catalase(CAT), oxidative damage(malondialdehyde, MDA) and apoptosis-related genes(nrf2, p53 and c-jun) of adult zebrafish after exposing to different AsⅢ concentrations(0, 10, 50, 100 or 150 μg L-1)for 28 d. Results indicated that exposure to low AsⅢ concentrations decreased the zebrafish weight by 14%, increased the activities of SOD and CAT by 23-41% and31-59%, decreased the contents of MDA by 29-54%, and modulated transcription of apoptosis related genes. Our study showed that chronic exposure to AsⅢ concentrations < 150 μg L-1 generated oxidative stress and damage on zebrafish, and altered apoptosis-related genes in zebrafish.更多还原