【作者】 周娜； 霍方俊；

【Author】 Na Zhou;Fangjun Huo;Institute of Molecular Science,Shanxi University;

【机构】 山西大学应用化学研究所；

【摘要】 本文设计了一种异噁唑加速型可快速与硫化氢响应的荧光探针。由于异噁唑的引入,加速了硝基与硫化氢之间的氧化还原反应,与已报道的硝基识别硫化氢探针相比响应时间缩短了十几倍至几十倍,只需55秒。同时该探针被成功地应用于检测HepG-2细胞的内、外源硫化氢。更多还原

【Abstract】 A isoxazole-accelerated fluorescent probe was designed that responds rapidly to H₂S. Due to the introduction of isoxazole, the redox reaction between the nitro group and H₂S is accelerated, and the response time is shortened by a factor of ten to several tens of times compared with the reported nitro-identified probe,only needs 55 s.. At the same time, the probe was successfully applied to detect endogenous/exogenous H₂S in HepG-2 cells.更多还原