The application of electrochemical sensor based on Zn-BTC@AuNPs composite material for simultaneous detection of dopamine and uric acid

【作者】 张万庆； 段大伟； 王吉超； 崔乘幸； 侯玉霞； 华抗； 张裕平； 屈凌波；

【Author】 Wan-qing Zhang;Da-wei Duan;Ji-chao Wang;Cheng-xing Cui;Yu-xia Hou;Kang Hua;Yu-ping Zhang;Ling-bo Qu;School of Chemistry and Chemical Engineering, Henan Institute of Science and Technology;College of Food Science and Technonlogy, Henan University of Technology;

【机构】 河南科技学院,化学化工学院； 河南工业大学,粮油食品学院；

【摘要】 In this paper,a new type of electrochemical sensor that can be used to detect DA and UA was prepared.The Zn-BTC@AuNPs nanocomposite was used as the electrode surface modification material.Zn-BTC material was firstly prepared by simple hydrothermal synthesis method,and then mixed evenly with chlorauric acid （HAuCl₄） solution.A layer of Zn-BTC@AuNPs nanocomposite film was formed on the electrode surface by electropolymerization.The electrochemical performance of Zn-BTC@AuNPs/GCE sensor was investigated by cyclic voltammetry （CV）,differential pulse voltammetry （DPV） and electrochemical impedance spectroscopy （EIS）.At the same time,the effects of polymerization potential,scanning rate and pH on the recognition of target molecules were also studied.Under optimal conditions,the sensor has high sensitivity and good discrimination effect on DA and UA.In addition,the peak value of the DPV current of the Zn-BTC@AuNPs/GCE sensor is linearly correlated with the concentration of DA and UA （0.1–800μM and 5-800μM,respectively）,and shows good reproducibility and stability.Finally,the sensor has been successfully applied to the determination of DA and UA in actual samples,and has a good recoveries.更多还原

【Abstract】 In this paper,a new type of electrochemical sensor that can be used to detect DA and UA was prepared.The Zn-BTC@AuNPs nanocomposite was used as the electrode surface modification material.Zn-BTC material was firstly prepared by simple hydrothermal synthesis method,and then mixed evenly with chlorauric acid （HAuCl₄） solution.A layer of Zn-BTC@AuNPs nanocomposite film was formed on the electrode surface by electropolymerization.The electrochemical performance of Zn-BTC@AuNPs/GCE sensor was investigated by cyclic voltammetry （CV）,differential pulse voltammetry （DPV） and electrochemical impedance spectroscopy （EIS）.At the same time,the effects of polymerization potential,scanning rate and pH on the recognition of target molecules were also studied.Under optimal conditions,the sensor has high sensitivity and good discrimination effect on DA and UA.In addition,the peak value of the DPV current of the Zn-BTC@AuNPs/GCE sensor is linearly correlated with the concentration of DA and UA （0.1–800μM and 5-800μM,respectively）,and shows good reproducibility and stability.Finally,the sensor has been successfully applied to the determination of DA and UA in actual samples,and has a good recoveries.更多还原