Lysine-specific demethylase 1 in the breast cancer cells contributes to the production of endogenous formaldehyde in metastatic bone cancer pain model of rats

【作者】 刘佳； 刘风雨； 童志前； 陈文； 蔡捷； 廖斐斐； 万有；

【Author】 Jia LIU;Feng-Yu LIU;Zhi-Qian TONG;Wen CHEN;Jie CAI;Fei-Fei LIAO;You WAN;Neuroscience Research Institute and Department of Neurobiology, Peking University;

【机构】 Neuroscience Research Institute and Department of Neurobiology, Peking University；

【摘要】 <正>Objective:Bone cancer pain seriously affects the quality of life of cancer patients.Our previous study found that endogenous formaldehyde was produced by cancer cells metastasized into bone marrow and played an important role in bone cancer pain.However,the mechanism of production of this endogenous formaldehyde by metastatic更多还原