【作者】 何建； 刘强；

【Author】 Jian He;Qiang Liu;State Key Laboratory of Applied Organic Chemistry, Lanzhou University;

【机构】 功能有机分子化学国家重点实验室,兰州大学；

【摘要】 环丁烷类是许多生物活性天然产物的重要结构成分,也是制备大环体系的重要合成中间体。[1]例如,马来酰亚胺衍生物的[2+2]环加成反应在合成化学、材料化学等领域具有不可替代的作用。通常该类化合物的[2+2]环加成反应需通过紫外光照射实现,在制备中对光反应设备有特殊要求。[2]因此,发展这类化合物的可见光催化反应十分必要。但是,常见的可见光催化剂由于三线态激发态能量较低,无法有效催化马来酰亚胺环加成。因此,我们通过对配体进行修饰,设计了具有较高三线态激发态能量的Ir(Ⅲ)配合物,并以其为光催化剂实现了可见光照射下马来酰亚胺衍生物和多种烯烃的[2+2]环加成反应。更多还原

【Abstract】 Cyclobutanes are important structural components in many bioactive natural products and are also valuable synthetic intermediates in the preparation of larger-ring systems. For example, [2 + 2] cycloaddition reaction of maleimide derivatives has an irreplaceable role in the field of synthetic chemistry and material chemistry. Normally, the [2 + 2] cycloaddition reaction of this kind of compound has to be realized by ultraviolet light, and there are special requirements for photoreaction equipment in the preparation. Therefore, it is necessary to develop the visible catalytic reaction of these compounds. However, visible-light driven [2 + 2] cycloaddition of maleimide derivatives were never reported,because the common visible photocatalyst can not effectively catalyze the cycloaddition due to the low energy of triplet state excitation. In this context, we designed higher triplet excited state energy of Ir(III)-based complexes as the candidate photocatalysts to achieve [2 + 2] cycloaddition between maleimide derivatives and a variety of olefin under visible light via energy transfer processes.更多还原