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基于非牛顿MPS方法的血小板血栓三维介观数值模拟
A Mesoscopic Simulation of Pale Thrombus by Non-Newtonian MPS Method
【Author】 Hao Xiang;Bin Chen;State Key Laboratory of Multiphase Flow in Power Engineering, Xi’an Jiaotong University;
【机构】 西安交通大学动力工程多相流国家重点实验室;
【摘要】 本文将血小板简化为单个粒子的模型,血小板的聚集和吸附通过弹簧模型实现,红细胞则由1个核粒子与20个吸附粒子通过多弹簧模型连接而成,基于非牛顿移动粒子半隐式方法(Moving Particle Semi-implicit method,MPS)建立了血小板血栓形成的三维介观血液流变学粒子法数值模型。该模型生成红细胞过程简单,且能够比较准确地模拟血小板和红细胞的形状特征和尺寸差异。使用该模型模拟了直管中血小板血栓形成的问题。通过与前人计算模型的对比,证明本文提出的血小板血栓形成介观模型并可显著提高计算效率。
【Abstract】 A mesoscopic particle model for the formation of the pale thrombus was developed based on the non-Newtonian MPS method. Platelet was modeled as rigid particle, and Red Blood Cell(RBC) was composed of 1 kernel particle and 20 adhesive particles. By using spring model to simulate the adhesion and aggregation forces between platelets, the present model can distinguish the shape and size of the platelet and RBC accurately, with advantage of simple formation of RBC. The formation of the pale thrombus in a 3 D straight vessel was simulated successfully.
【Key words】 pale thrombus; red blood cell; platelet; spring model; moving particle semi-implicit method;
- 【会议录名称】 第十三届全国流变学学术会议论文集
- 【会议名称】第十三届全国流变学学术会议
- 【会议时间】2016-10-23
- 【会议地点】中国陕西西安
- 【分类号】O373;R318
- 【主办单位】中国化学会、中国力学学会流变学专业委员会