Digging the Metabolic Potential of a Deep-sea Derived Fungus Penicillium sp.F23-2

【作者】 郭文强； 杜林； 朱天骄； 车茜； 顾谦群； 李德海；

【Author】 Wenqiang Guo;Lin Du;Tianjiao Zhu;Qian Che;Qianqun Gu;Dehai Li;Key Laboratory of Marine Drugs,Chinese Ministry of Education,School of Medicine and Pharmacy,Ocean University of China;

【机构】 Key Laboratory of Marine Drugs,Chinese Ministry of Education,School of Medicine and Pharmacy,Ocean University of China；

【摘要】 <正>Surviving in unique ecological environment,the deep-seaderived microorganisms were proved to producediverse novel chemical structures and biological activities of microbial secondary metabolites,which demonstrated exceptional potency in drug discovery as new drug leads.^1,2Although thousands of compounds with various chemical structures have been disclosed,most of the gene clusters更多还原