Tim-3 Inhibits the Macrophage Activity In Echinococcus granulosus Infected Mice

【作者】 Fangjie Xu； Jun Hou； Shuanghong Yin； Hairui Fang； Hongqun Jiang； Xiangwei Wu； 陈雪玲；

【Author】 Fangjie Xu;Jun Hou;Shuanghong Yin;Hairui Fang;Hongqun Jiang;Xiangwei Wu;Xueling Chen;Department of Immunology, School of Medicine, Shihezi University;

【机构】 石河子大学医学院免疫学教研室；

【摘要】 <正>Introduction:To understand the expression levels of Tim-3,a new proinflammatory factor in the early stages of Echinococcus granulosus infection in mice.Through the establishment of animal models of Echinococcus granulosus(E.granulosus)infected mice,we explored whether E.granulosus promote Tim-3 up regulation on the macrophage,and then inhibits its activity.更多还原