【作者】 刘新愚； 郝红伟； 王唯霖； 刘敏； 赵文；

【Author】 LIU Xin-yu;HAO Hong-wei;WANG Wei-lin;LIU Min;ZHAO Wen;College of Food Science and Technology,Agricultural University of Hebei;

【机构】 河北农业大学食品科技学院；

【摘要】 目的:研究骏枣膳食纤维改善功能性便秘的保健功效。方法:以昆明种小鼠为实验对象,随机分为5组,即溶剂对照组、便秘模型组和低(0.25g/kg·d)、中(0.5g/kg·d)、高(1.0g/kg·d)3个枣膳食纤堆剂量组。用上述剂量的枣膳食纤维灌胃10d后建立功能性便秘模型,观察枣膳食纤维对小鼠小肠推进率、排便时间和排便质量的影响。结果:枣膳食纤维可提高小鼠的小肠推进率,且中、高剂量组与便秘模型组有极显著性差异(P<0.01);枣膳食纤维还可缩短小鼠首粒排黑便时间和增加排便质量,且低剂量组具有显著性差异(P<0.05),中、高剂量组具极显著性差异(P<0.01)。结论:枣膳食纤维在500mg/kg·d的剂量条件下对小鼠具有显著的润肠通便功效,可有效改善功能性便秘。更多还原

【Abstract】 Objective:To explore the ameliorative effect of jujube dietary fiber(JDF) on functional constipation.Methods-.Mice were randomly divided into 5 groups including blank control group,constipation model group and JDF groups at the low,middle and high doses.Functional constipation model was established after oral administration of jujube dietary fiber for 10 d.The intestinal motion rate,defecation time and feces weight of all the mice were investigated.Results;The motional rate of ink in the intestine was enhanced by JDF administration,and there were significant differences(P<0.01) between middle、high dose and constipation model group.Jujube dietary fiber also can abridge the initial defecation time and increase total feces weight when compared to the constipation model group.Conclusion:The administration of SOOmg/kg ·d of jujube dietary fiber has effective defecation-promoting in mice,which is beneficial for relieving functional constipation.更多还原