【作者】 赵嘉祥； 关雁飞； 陈学国； 宋辉； 许英健；

【Author】 Zhao Jiaxiang~1,Guan Yanfei~2,Chen Xueguo~1,Song Hui~1,Xu Yingjian~1 (1.Department of Forensic Medicine,China Criminal Police University,Shenyang 110854; 2.City branch of Changzhi Public Security Bureau,Changzhi 046000)

【机构】 中国刑事警察学院法化学系； 山西省长治市公安局城区分局；

【摘要】 建立了离子液体分散液液微萃取高效液相色谱分析方法并用于尿中曲马多的分析。实验结果表明:曲马多在0.5～200μg/mL浓度范围内具有良好的线性关系,检出限为0.2μg/mL,最佳萃取条件下,曲马多的富集因子为89。所建立的方法具有简便、环保、试剂用量少、富集倍数高等特点。更多还原

【Abstract】 A method for the analysis of tramadol in urine using ionic liquid based liquid-liquid extraction coupled with high-performance liquid chromatography has been investigated. The results indicated that good linear ranges were obtained with 0.5～200μg/mL,the detection limits was 0.2μg/mL,and the enrichment factor was 89.The results also showed that ionic liquid based high-performance liquid chromatography method is simpler,requires fewer amounts and has higher extraction efficiency.更多还原