妊娠前后规范化抗梅毒治疗对胎传梅毒的影响

【作者】 黄跃斌； 何印蕾；

【机构】 右江民族医学院；

【摘要】 目的探讨育龄妇女妊娠前后规范化抗梅毒治疗对阻断胎传梅毒效果的影响。方法对受孕前已经规范化抗梅毒治疗的孕妇及其新生儿进行梅毒血清学TRUST滴度和TPHA检查,并与妊娠期梅毒孕妇及其新生儿进行比较。结果妊娠梅毒检出率为2.06%,先天梅毒儿检出率为0.45%;妊娠梅毒的孕妇规范化治疗后疗效明显,TRUST滴度明显下降。受孕前规范化抗梅毒治疗后的梅毒胎传率明显低于妊娠梅毒孕妇的胎传率,两组比较差异有统计学意义(P<0.01)。结论妊娠前进行梅毒血清学筛查,以便规范化抗梅毒治疗,有效阻断母婴垂直传播,对育龄妇女妊娠结局有很好的意义。更多还原

【Abstract】 Objective: To explore the effect of standardized anti- syphilis treatment for blocking congenital syphilis with pre and post pregnancy in women of childbearing age. Methods: To testing syphilis serology Tolulized Red Unheated Serum Test titer and Trepomema Palidum Hmagglutination Assay for standardized anti- syphilis treatment of pre pregnancy and their newborn,and compare with syphilis in pregnant women and their newborn. Results: The detection rate of syphilis in pregnancy were 2. 06%,The congenital syphilis incidence in all of observed newborns were 0. 45%. The TRUST titer decreased of syphilis in pregnant women after standardized anti- syphilis treatment. The congenital syphilis incidence of pre pregnancy women significantly lower than the syphilis in pregnant women( P < 0. 01). Conclusion: Screening of syphilis for standardized anti- syphilis treatment of pre pregnancy,can effectively block mother- to- child transmission and obviously improve the outcome of pregnancy for women of childbearing age.更多还原