【作者】 李惠惠； 吴霞；

【Author】 LI Hui-hui;WU Xia;School of Chemistry and Chemical Engineering,Shandong University;

【机构】 山东大学化学与化工学院；

【摘要】 银纳米粒子具有独特光学性质,其结构表面等离子体共振所产生局域场强度的变化会引起吸附于颗粒表面及周围荧光团的自由空间条件的改变,从而影响吸附于纳米银表面荧光团的发光特性。研究发现,银纳米粒子存在下Tb(Ⅲ)-Gd(Ⅲ)-多巴胺(DA)稀土离子共发光效应,建立了灵敏的测定多巴胺分析方法。实验结果表明:银纳米粒子可显著增强Tb(Ⅲ)-Gd(Ⅲ)-DA体系的荧光强度。在最佳实验条件下,体系的荧光强度与多巴胺浓度在一定范围内呈线性关系。将该方法用于盐酸多巴胺注射液中多巴胺的测定,获得满意结果。更多还原

【Abstract】 A simple,sensitive and selective fluorescence detection method for the determination of dopamine（DA） is proposed based on co-luminescence effect of rare earths in the presence of silver nanoparticles（AgNPs）.It is found that DA can remarkably enhance the luminescence intensity of the Tb³⁺ ion by the co-luminescence ion(Gd³⁺) in the colloidal solution of AgNPs.Under the optimized condition,the luminescence intensity of the system is linearly related to the concentration of the DA with range of 5.0¹00 nmol·L^-1,with a limit of detection（S/N=3）as low as 1.7 nmol·L^-1.The proposed method is applied successfully for the determination of DA in injections of pharmaceutical preparations.更多还原