【作者】 徐秦峰； 张敏； 薛冰纯； 韩素琴； 柴宜民； 刘二保；

【Author】 XU Qin-feng,ZHANG Min,XUE Bing-chun,HAN Su-qin,CHAI Yi-min,LIU Er-bao~* College of Chemistry and Material Science,Shanxi Normal University,Linfen 041004,China

【机构】 山西师范大学化学与材料科学学院；

【摘要】 采用流动注射技术,在H₂O₂-Na₂CO₃-NaOH反应介质中,对氯化血红素在紫外光、自然光作用下分解情况及药片中氯化血红素的含量进行了研究。结果发现氯化血红素在不同光作用下分解反应速度不同,但其光解均为一级反应。将氯化血红素样品避光,测定氯化血红素的线性范围是2.2×10^-10～6.88×10^-7mol·L^-1,检出限（3σ）为2.2×10^-11mol·L^-1。此法直接用于药物中氯化血红素的分析。更多还原

【Abstract】 Using hydrogen peroxide-carbonate-sodium hydroxide medium,the study on the photodeoomposition behavior of hemin under ultraviolet light and solar light were carried out and the determination of hemin was developed coupled with simple flow injection technique.The results showed that the decomposition reaction of hemin in different light irradiations corresponded with a first-order reaction.And then the determination of hemin was completed.The detection limit was 2.2×10^-11 mol·L^-1（3σ）.The relative standard deviation was 2.82%for ten independent detections of 1.72×10^-8 mol·L^-1 hemin.As a preliminary application,the proposed method was successfully applied for the analysis of hemin in pharmaceutical formulations.更多还原