【作者】 张进治； 汪瑗； 李丽华；

【Author】 ZHANG Jin-zhi~1,WANG Yuan~2,LI Li-hua~1 1.North University of Technology,Beijing 100041,China 2.Capital Normal University,Beijing 100037,China

【机构】 北方工业大学理学院； 首都师范大学化学系；

【摘要】 <正>1学术贡献应用表面增强拉曼光谱技术将薄层色谱与FT-Raman光谱联用,获得抗菌素磺胺类药物的有效成分磺胺甲基异恶唑光谱的新方法。研究表明,在薄层原位仅1μg样品就可获得分子的主要振动谱带。阐明了应用表面增强拉曼光谱技术将薄层色谱与FT-Raman光谱联用对医药化学成分进行高灵敏度检测的可行性及优越性。2研究意义通过近几年的研究,我们认为解决中药指纹图谱的可行办法是:TLC和SERS的结合。因为薄层层析(Thin LayerChromatography,TLC)是一种简便、快速、准确、微量的定更多还原

【Abstract】 A new method is given in this paper to get the spectra of sulfamethoxazole,which is the efficient ingredients of sulfanilamide -like medicine,by using the surface enhanced Raman spectroscopy technology to unite the TLC and FT-Raman spectroscopy. The result indicates that the main vibrant characteristic spectral band can be obtained by TLC in the samples of about 1μg.The analysis shows that the method of union of TLC and FT-Raman spectroscopy by the SERS is practical and advantageous in the highly sensitive inspection to the chemical ingredients of medicine.更多还原