【作者】 叶邦策； 张闽； 尹斌成； 刘玉强；

【Author】 Bang-Ce Ye,Min Zhang,Yin Bin-Cheng,Yu-Qiang Liu State Key Laboratory of Bioreactor Engineering,East China University of Science & Technology,Meilong Road 130,Shanghai,200237,China

【机构】 生物反应器工程国家重点实验室华东理工大学；

【摘要】 <正>利用生物分子特异性识别或催化活性和纳米粒子独特的性质组装形成的生物纳米探针在临床诊断、食品和药物分析、环境保护以及生物技术、生物芯片等领域的研究和应用成为当前国内外的研究热点。本研更多还原

【Abstract】 The emergence and recent advance of nano-science and nano-technology provide new opportunities for the application of nano-materials in biochemical analysis.The marriage of nano-materials and biochemical molecules to form novel nano-bio probes has great potential for biochemical analysis applications,such as clinic diagnosis,food and drug analysis,environmental protection,and so on,which integrates both the unique structural and photophysical features of nano-materials and the fascinating properties of biochemical molecules.In this study,we combined nanotechnology with biological molecules engineering technology to develop the new biological detection methods involved function biological molecules(such as: nucleic acid,polypeptide) as recognition components.Some colorimetric probes have been presented for biochemical applications utilizing metal nanoparticles as color indicator,such as water quality evaluation(SO 4 2),heavy metal ion pollution monitoring(Ag +,Hg 2+,Cd 2+,Co 2+ and Ni 2+),the rapid detection of pollutants in food(phthalates),and chiral enantiomer discrimination and separation(cysteine) and colorimetric detection of aluminium(III) on living cellular surfaces.更多还原