【作者】 陈川； 郭祥群；

【Author】 Chen Chuan,Xiangqun Guo The Key Laboratory for Chemical Biology of Fujian Province,Department of Chemistry and The Key Laboratory of Analytical Sciences,College of Chemistry and Chemical Engineering,Xiamen University,Xiamen 361005

【机构】 福建省化学生物学重点实验室厦门大学化学化工学院化学系分析科学重点实验室；

【摘要】 <正>成像技术是疾病诊断的重要手段之一。不同的成像技术各具优势和不足,单一模式的探针难以应对多指标检测和协同成像的需求。多模式体内成像技术,可对患者的异常部位进行活体可视化动态成像,对病更多还原

【Abstract】 In the present work,we developed a new Multifunctional probe by spin-labeling of upconversion fluorescent nanoparticles.4-Amino-TEMPO nitroxide radical was covalently linked with Oleic acid on the surface of upconversion fluorescent naonoparticles to produce a spin-labelled multifunctional probe,which means that this nanoparticles is promising as a kind of new stable multi-modal(fluorescence and MRI)probe.更多还原