【作者】 徐国宾； 陈应； 潘鑫渊； 聂磊； 杨原；

【Author】 Guobin Xu 1,2,Ying Chen 3,Xinyuan Pan 3,Lei Nie 2,Pengyuang Yang 1,2, 1 Department of Chemistry,Fudan University,Chem Bld W.219,Handan Rd.220,Shanghai,200433 1 Institute of bio-medical science,Fudan University,Mingdao Bld.Dongan Rd.130,Shanghai,200032 2 Institute of environment and chemical engineering,Shanghai University,Shangda Rd.99,Shanghai,200444

【机构】 复旦大学化学系； 复旦大学生物医学研究院； 上海大学环境与化学工程学院；

【摘要】 <正>LIT-TOF通过在自行研制的高分辨飞行时间质谱上,巧妙的改进现有离子传输部件,增加高精度射频电源、辅助射频电源和离子阱控制卡等,达到多级串联质谱的功能,在生物医药分析领域具有良好前景。其LIT部更多还原

【Abstract】 A novel LIT-TOF is designed based on our lab-made oaTOF-MS.The ion guide system is upgraded with high precision radio-frequency source,auxiliary waveform and ion trap control card to form a simple linear ion trap utilizing the existing quadrupole ion guide parts.The LIT section has an m/z range of 30~2500u and parent ion selection window of 3~50u.The TOF section,using high speed ADC card,has a resolution of 12000 FWHM.With effective tandem stage of 5,this device is suitable for both LCMS and GCMS application.However,the sensitivity of MS2 is low compared to QTOF.更多还原