【作者】 刘志东； 陈雪忠； 黄洪亮； 李灵智；

【Author】 Liu Zhi-dong, Chen Xue-zhong, Huang Hong-liang * , Li Ling-zhi (East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090,China)

【机构】 中国水产科学研究院东海水产研究所；

【摘要】 南极海洋生物在漫长的进化过程中为免受低温和氧化应激的伤害形成了冷适应功能。"海洋来源生育酚"(MDT)是一类特殊的维生素E同系物。研究表明MDT提高了海洋生物细胞中脂质的抗氧化保护功能,增加了不同脂质在低温时的扩散速率。南极冰鱼的内收肌比白色的肌节肌肉含有更高的维生素E,但是MDT组成差异却很小。南极磷虾和浮游植物的也含有MDT,这些支持了MDT直接来自南极海洋生物初级食物链的观点。因此,南极海洋生物的MDT与其抗氧化和低温的冷适应功能的假定相一致,并且这种冷适应机制能够在南极海洋生物的初级食物链中进行生物传递。更多还原

【Abstract】 The marine organisms of Antarctica have developed cold-adapted functions to protect themselves against low temperature and oxidative stress. "Marine-derived tocopherol" (MDT) as a specific vitamin E homologue is an unusual methylene unsaturation at its isoprenoid-chain terminus of the tocopherol molecule. MDT was found to co-exist with α-tocopherol in all Antarctic samples, ranging from 2.8 to 22.3% of the total vitamin E composition. MDT provides empirical confirmation that the enhanced antioxidant protection of cellular lipids and its greater rate of diffusion in viscous lipids at low temperature. Moreover, the pectoral adductor muscle in notothenioids, which has a high density of mitochondria, contained higher levels of Vitamin E than white myotomal muscle, but differences in MDT composition were small. Phytoplankton and krill also contained MDT, which supports the point of view that MDT is obtained directly from the primary food chain of the marine organisms of Antarctica. Our finding of MDT from Antarctica is consistent with its putatively cold-adapted function to enhance antioxidant protection against low temperature, and the cold-adapted mechanisms underlying the biological transformation in the primary food chain of the marine organisms of Antarctica.更多还原