Virtual Screening of Selective Multi-Target Kinase Inhibitors by Combinatorial Support Vector Machines

【作者】 陈宇综；

【Author】 Yu Zong Chen*, Xiao Hua Ma, Xiang Hui Liu Bioinformatics and Drug Design Group, Department of Pharmacy, Center for Computational Science and Engineering, National University of Singapore, Singapore 117543

【机构】 Bioinformatics and Drug Design Group, Department of Pharmacy, Center for Computational Science and Engineering, National University of Singapore；

【摘要】 <正>Multi-target agents have been increasingly explored for enhancing efficacies and reducing counter-target activities and toxicities. Efficient virtual screening (VS) tools for searching selective multi-target agents are desired. Based on our earlier studies [1-3], we have更多还原