【作者】 乃海燕； 毕津莲； 李湘斌；

【Author】 Nai Haiyan, Bi Jinlian,Li Xiangbin(Dept. of Pharmacy, The First Affiliated Hospital of Nanhua University,Hengyang 421001, Hunan, China)

【机构】 南华大学附属第一医院药剂科；

【摘要】 目的:了解我院门诊抗高血压药物的使用情况。方法:采用世界卫生组织推荐的限定日剂量、药物利用指数等方法,对我院2009年1月门诊处方抗高血压药的使用情况进行统计、分析。结果:各年龄组间的高血压患病率存在显著性差异,其随年龄的增长而显著增加。钙拮抗剂、血管紧张素Ⅱ受体拮抗剂(ARB)、血管紧张素转换酶抑制剂(ACEI)的使用频率最高。联合用药占全部处方40.94%,其中以二联用药为主。结论:我院抗高血压药应用基本符合2005年版《中国高血压防治指南》。单药治疗以第3代钙拮抗剂、ARB、长效ACEI为主。大部分联合用药方案较合理,但也存在一些重复用药行为,须引起临床医生重视。更多还原

【Abstract】 OBJECTIVE:To probe into the situation of the use of antihypertensive d rugs in our hospital. METHODS: The use of antihypertensive drugs in our hospital during the January of 2009 was analyzed statistically by using definite daily dose(DDD) and DUI recommended by WHO as indicators. RESULTS: The differences between different age group in respect of incidences of hypretension were significant and increased with the increase of age.The most frequently prescribed anti-hypertensive drugs were calcium channel blocker, Angiotensin-II receptor antagonist and angiotensin converting enzyme inhibitor(ACEI). The rate of drug combination accounted for 40.94% of the total prescriptions, most of which were combination of two drugs. CONCLUSION: The utilization of antihypertensive drugs in our hospital was basically in line with China Guidelines on Prevention and Man-agement of High Blood Pressure. The Third generation calcium channel blocker,ARB and ACEI with prolonged action took the lead among the monotherapy. Most of the drug combination therapies were rational, but there were cases of repeated use of drugs, which call for great attention in the clinic.更多还原