【作者】 卢敏； 金纯； 郑晨果；

【Author】 LU Min~1 JIN Chun~1 ZHENG chen-guo~1 zhouxuan~2 (1 Department of Chinese-wernsten’s rectal-anal,2 Department of medicament,The second hospital Affiliated with WenZhou Medical College and University;325027;China)

【机构】 温州医学院附属第二医院中西医结合肛肠科；

【摘要】 目的:观察"丹参枳术饮"的急慢性毒性反应。方法:ICR小鼠40只,随机分为2组,观察用"丹参枳术饮"灌胃后的小鼠的急性毒性反应;SD大鼠40只,随机将动物分配为4组,分为高、中、低剂量组和对照组各10只,观察用丹参枳术饮连续灌胃4周后的大鼠慢性毒性反应。结果:急慢性毒理实验均未发现明显的毒副作用。结论:"丹参枳术饮"是一种低毒的中药方剂,用于临床是安全的。更多还原

【Abstract】 Objective:To observe the acute and chronic toxicity of DSZSY.Methods:Forty healthy ICR mice were divided into two groups randomly for the acute toxic reaction after drug was given by affusing stomach.;Forty healthy SD rats were divided into four groups includes high-dose,middle-dose,slight-dose and control groups randomly for the chronic toxic reaction after drug was given by affusing stomach.Results:DSZSY doesn’t cause any toxic and chronic reaction on mice.Conclusion:DSZSY is a low-toxicity and relatively safe drug.更多还原