【作者】 吴达旭； 施继成； 卢葛覃； 康北笙；

【Author】 Wu Daxu Shi Jicheng Lu Getan Kang Beisheng (State Key Laboratory of structural Chemistry,Fujia Institute of Research on the Structure of Matter,Chinese Academy of Sciences,Fuzhou,350002)

【机构】 中国科学院福建物质结构研究所结构化学国家重点实验室；

【摘要】 <正>我们知道,手性膦配体常常用于对映体选择催化反应中,而且在生物催化和医药方面有着广阔前景.我们制备了两种手性膦配体:甲基-3-脱氧-3-(二苯膦基)-4,6-氧-苄叉基-α-D-吡喃阿卓糖苷(3-MBPA)和甲基-2-脱氧-2-(二苯膦基)-4,6-氧-苄叉基-α-D-吡喃阿更多还原

【Abstract】 Chiral phosphines are useful ligands inenatioselective catalysis with transition metal compounds.They also are potential application in biophsiccatalysis and medicine.We prepare two new chiral phosphine ligands:methyl 3-deoxy-3- （diphenylphosphino）-4,6-O-benzylidene-α-D-altro- pyranosid （3- MBPA） and methyl 2-deoxy-2-（diphenylphosphino）-4,6-O- benxylidene-α-D-altropyranoside（2-MBPA）.They were treated with（Rh（CO）₂Cl）₂ to give yellow rhodium compounds,which are trans-（（3-MBPA）₂Rh（CO）Cl） （1）and trans-（（2-MBPA）₂Rh（CO）Cl） （2）. In this paper,2D NMR（H-H COSY,H-C HMQC and HMBC Spectra） techniques were used to analyze and assign the ¹H and ¹³C NMR spectra,and the coupling constants (J_PRh=122.8Hz,126.7Hz) indicate that the rhodium compounds are trans geometry.更多还原