【作者】 霍霞； 李燕； 徐锡金； 吴库生； 刘俊晓； 陈松建； 陈刚建；

【Author】 Xia Huo Yan Li Xijin Xu Kusheng Wu Junxiao Liu Songjian Chen Gangjian Chen (Analytical Cytology Laboratory and the Key Immunopathology Laboratory of Guangdong Province,Shantou University Medical College,Shantou 515041,China)

【机构】 汕头大学医学院分析细胞学实验室；

【摘要】 广东汕头贵屿镇有着近20年的电子垃圾回收拆解历史,简单落后不规范的电子垃圾拆解方式使环境中多种有毒物质尤其是重金属如铅、镉和铬含量严重超标。本实验目的是检测当地新生儿脐带血铅、镉和铬负荷并调查新生儿出生情况。用石墨炉原子吸收光谱法检测贵屿当地289例新生儿和邻近贵屿的潮南地区134例新生儿脐带血铅、镉和铬水平。采用回顾性调查方式,以厦门郊区数据为对照调查2001-2007年贵屿地区产妇及新生儿的生育和出生情况。结果表明贵屿地区新生儿脐带血铅、镉和铬水平明显高于潮南地区(P<0.01)。贵屿当地新生儿的早产、死胎、低体重儿、双胎等异常出生情况明显高于厦门对照地区。表明贵屿地区新生儿铅、镉和铬暴露对新生儿的生长发育已经造成不良影响。更多还原

【Abstract】 Guiyu is a major electronic waste(e-waste) recycling town in China.Various environmental harmful substances especially poisoning heavy metals such as lead,cadmium and chromium in soaring levels by primitive and uncontrolled e-waste recycling,which may lead to adverse birth outcomes.The aim of this study was to quantify prenatal exposure to lead,cadmium and chromium with increasing risk of adverse birth outcomes in Guiyu.A total of 289 neonates from Guiyu and 134 neonates from the neighboring town named Chaonan were selected for the measurement of lead,cadmium and chromium levels in their umbilical cord blood with Graphite furnace atomic absorption spectrometry(GFAAS).In addition,a retrospective analysis on neonatal birth outcomes in Guiyu was performed.Birth record data were obtained from the hospitals for all registered births in an e-waste recycling town,Guiyu of Shantou,Guangdong province(Guiyu,n=3578) and Xiamen suburban areas of Fujian province,not related to e-waste (n=12384) from 2001 to 2007.Compared with Chaonan,neonates in Guiyu had significantly higher levels of lead,cadmium and chromium in the umbilical cord blood(P<0.01).The rates of preterm delivery,fetal death,twins and low birth weight in Guiyu group were all higher than those of Xiamen(P<0.01).This study provides evidence that combined exposure to lead,cadmium, and chromium from the primitive and unregulated e-waste processing increases the risk of adverse birth outcomes and adversely affects fetal health and development.更多还原