【作者】 刘燕； 阎永胜； 尹盛； 姜廷顺； 王坤；

【Author】 LIU Yan YAN Yong-sheng YIN Sheng JIANG Ting-shun WANG Kun~* (College of Chemistry and Chemical Engineering,Jiangsu University,Zhenjiang 212013)

【机构】 江苏大学化学化工学院；

【摘要】 <正>多巴胺(DA)和抗坏血酸(AA)是重要的生物医学化合物,准确测定二者的浓度在神经化学和生物分析领域都具有重要的意义。但由于两者在一般固体电极上的氧化峰电位靠近,相互干扰严重,因此选择合适的修饰电极将二者的氧化峰有效地分开,实现对其同时测定,一直是生物电分析工作者感兴趣的问题之一。更多还原

【Abstract】 A novel nanosize cobalt mesoporous molecular sieve （nCoMCM-41）modified glassy carbon electrode （GC） has been fabricated by a simple embeded method using chitosan as disperser.It was used to electrochemically detect （AA）,dopamine （DA）by cyclic voltammetry （CV）and differential pulse voltammetry （DPV）method.With potential difference of 310 mV and the peak current enhanced compared of bare GC,the potential difference is large enough to detennine AA and DA simultaneously.On optimal conditions,the good linear response to AA and DA was observed in the range of 8.0×10^-7～1.2×10^-3mol/L and 4.4×10^-6～5.0×10^-3mol/L,with the correlation coefficient of 0.9966 and 0.9976,respectively.The CoMCM-41 modified electrode can be used as a biosensor with high selectivity, sensitivity and detection of submicromolar concentrations of ascorbic acid and dopamine with practical applications to real samples.更多还原