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丙三醇缩水甘油醚改性脱细胞猪真皮基质的研究
Study on procine acellular dermal matrix modified by glycerol polyglycidyl ether
【作者】 但年华; 曾睿; 但卫华; 王亮; 林海; 关林波; 王康建; 米贞健;
【Author】 DAN Nian-hua~(1,3) ZENG Rui~2 DAN Wei-hua~1 WANG Liang~1 LIN Hai~3 GUAN Lin-bo~1 WANG Kang-jian~4 MI Zhen-jian~4 (1.Key Laboratory of Leather and Engineering of Ministry of Education,Sichuan University,Chengdu 610065,China; 2.Institute of Light,Textile and Food Industry,Sichuan University,Chengdu 610065,China; 3.Jiangyin Benshine Biotechnology Ltd,Jiangyin 214400,China; 4.Chengdu Bailejing Biotechnology Ltd.,Chengdu 610065,China)
【机构】 四川大学皮革化学与工程教育部重点实验室; 四川大学轻纺与食品学院; 江阴奔翔生物科技有限公司; 成都佰乐金生物科技有限公司;
【摘要】 研究了丙三醇缩水甘油醚(GPE)改性脱细胞猪真皮基质材料(pADM)的基本性能.通过考察不同温度、pH 值、用量和反应时间对改性材料 (GPE-pADM)性能的影响,初步探讨了改性条件与改性材料性能之间的关系.实验结果表明:反应温度37~ 42℃,pH 位10.0~10.5,反应时间48~72h,用量8% 时综合性能较好.交联后材料的接触角明显降低,且随着 GPE 用量的增加,接触角降低程度增大,表明交联提高了材料的亲水性能.
【Abstract】 The basic performance of Procine acellular dermal matrix(pADM)were studied after modified by glycerol polyglycidyl ether.The relation between the modified material and properties of modified material was discussed preliminarily,through researching on performance of the GPE-pADM influenced by the different temperature,pH,dosage and reaction time.It is showed that the comprehensive performance was best when the reaction temperature was 37-42℃, the pH was 10.0-0.5,the reaction time was 48-72h and dosage was 8%.The contact angle of the crosslinked material was reduced obviously,and the more dosage of GPE was used,the more reduced extent of contact angle was.It is indicated that the hydrophilic performance of the material had been improved by cross-linking.
【Key words】 glycerol polyglycidyl ether; modification; procine acellular dermal matrix; collagen;
- 【会议录名称】 第六届中国功能材料及其应用学术会议论文集(9)
- 【会议名称】第六届中国功能材料及其应用学术会议
- 【会议时间】2007-11
- 【会议地点】中国湖北武汉
- 【分类号】TS51
- 【主办单位】重庆仪器材料研究所、中国仪器仪表学会仪表材料分会、国家仪表功能材料工程技术研究中心