【作者】 郭秀丽； 李祥龙； 周荣艳； 李兰会； 李艳琴；

【Author】 GUO Xiu-li,LI Xiang-long,ZHOU Rong-yan,LI Lan-hui,LI Yan-qin (College of Animal Science and Technology, Agricultural University of Hebei, Baoding, 071001)

【机构】 河北农业大学动物科技学院；

【摘要】 本文应用比较基因组学和生物信息学方法比较了GenBank中山羊、绵羊、牛、鹿和长臂猿MHC-DQA2基因部分序列,并分析了该基因的核苷酸及氨基酸多棒陛。结果表明,44 个基因序列检测到79个多态位点,共生成38个单倍型。物种间和物种内MHC-DQA2基因均存在丰富的核苷酸及氨基酸遗传多样性。更多还原

【Abstract】 In this study, part of MHC-DQA2 gene sequences of Capra hircus, Ovis aries, Bos taurus, Cervus nippon and Hylobates lar from GenBank were analyzed using the method of comparative genomics and bioinformatics. The nucleotide diversity and amino acid diversity were also studied. The results showed that a total of 79 polymorphic sites were detected from 44 sequences, from which 38 hapolotypes were sorted. More nucleotide diversity and amino acid diversity of MHC-DQA2 gene existed within and among species.更多还原