【作者】 江锦芳； 陈丽君； 劳永聪； 许璐； 李灿炎； 刘志民；

【Author】 Jing Jin-Fang Chen Li-Jun Lao Yong-Cong Xu Lu Li Can-Yan Liu Zhi-Min No.1 Chemotherapy Department of Tumor Hospital Subsidiary to Guangxi Medicine University , Nanning , 530021

【机构】 广西医科大学附属肿瘤医院化疗一科；

【摘要】 目的:化疗性口腔炎是化疗常见的副反应之一,较多的研究发现三七花和或三七花中所含的三七花皂甙具有局部消炎和治疗消化粘膜溃疡的作用。冷开水含漱是有效地预防及治疗恶性肿瘤化疗所致的口腔炎的常用方法之一。探讨口含三七花冰块预防化疗后口腔炎的作用。方法:将三七花 20克加入1000毫升中煮沸煎成700毫升～800毫升的三七花液,再装在小冰槽中通过冷却制成冰块,大小约3厘米×3厘米×2厘米;含漱液用朵贝尔氏液。两组患者化疗前均进行口腔状况进行评估,均无口腔炎。观察组:根据患者的情况给予相应的自我护理指导,给患者介绍化疗药物损伤口腔粘膜的原理及发生口炎的临床表现,并进行保持口腔卫生宣教, 正确的漱口方法指导,每日早、晚餐后刷牙各1次,呕吐后用朵贝尔氏液漱口,禁烟酒及刺激性食物。从化疗当日开始使用三七花冰块口含漱,每2小时1次,每日7次至化疗结束后五天。对照组:不用三七花冰块口含漱,化疗当日开始使用朵贝尔氏液含漱,每2小时1次,每天7次至化疗结束后五天,其它护理方法同观察组。两组病人一但发生口腔炎则按医嘱做局部用药及口腔炎护理常规进行。结果:观察组口腔炎发生率为8％,对照组的发生率为24％,观察组显著低于对照组。说明化疗病人口含三七花冰块更有效地预防口腔炎发生。另外,观察组口腔炎愈合时间较对照组显著缩短。但在本研究中,我们采取均采用自我护理方法,使病人主动参与。对化疗病人进行口腔炎自我护理指导,提供相应的支持和援助。调动了病人的主观能动性,如教会病友正确的漱口方法,向病人传授们所缺的口腔护理知识,呕吐后立即漱口,使病人明白为什么要做,懂得如去做,两组病人用同样的护理方法,其口腔炎的程度都较轻,并且轻重度对比无显著差异。结论:口含三七花冰块能较好的防治肿瘤患者化疗后口腔炎的发生。且主动参与的自我护理方法适宜于口腔护理。更多还原

【Abstract】 Objective: Chemotherapeutic mouth cavity phlegmonosis is one of the familiar adverse reaction in chemotherapy. Many research detection that sanchi flower or sanchi flower saponin extracted from sanchi flower have dephlogisticate function with treatment part dephlogisticate or digest mucous membrane ulcer.Mouthwash cold boiled waters is one of the availably prevent and cure mouth cavity phlegmonosis resulted from malignant tumor chemotherapy . Approach the function of sanchi flower ice-cubes preventions the mouth cavity phlegmonosis after chemotherapy. Methods: Put 20 grams into 1000 millili-ters water and decoct to 700-800 milliliters sanchi flower liquid, then pack it into small ice slot and cool turn into the ice-cubes. the ice-cubes size is roughly 3 ×3 ×2 entimter. GARG uses Borax liquid.Before chems, both the two team had been evaluated and detected having no the mouth cavity phlegmonosis .We introduct homologous ego discharge to the sufferer according to their condition, introducing the sufferer with the principle how the chemotherapy medicine hurts the oral mucosa and how the mouth cavity phlegmonosis occurrence ,introducing how keeps the mouth cavity hygiene and the rightly method of gargling. Everyday the sufferer brushes teeth after breakfast and supper .The sufferer gargl after vomit with Borax liquid, forbided smoking, wine and stimulating foods. The sufferer mouthwash sanchi flower ice-cubes since the day chemotherapy begins , once every 2 hours , 7 times per day, to 5th day after chemotherapy finish. Control group The sufferer mouthwash without sanchi flower ice-cubes but Borax liquid since the day chemotherapy begins , once every 2 hours, 7 times per day, to 5th day after chemotherapy finish. The other nursing method is the same like the Observe group. If any patient of the two tean had got mouth cavity phlegmonosis, they would had been cured and nursed routine in the term of mouth cavity phlegmonosis following doctor’s orders. Results: In observe group the occurrence rate of mouth cavity phlegmonosis is 8%, but the occurrence rate in the control group is 24%, the rate of observe team is significant lower than control group . Prove that the chemotherapy patient contain sanchi flower ice-cubeses can more availably prevent the mouth cavity phlegmonosis occurrence. Moreover, the mouth cavity phlegmonosis cuer time in observe group is shorter than which is in control group. But in this study, we all adopt ego nursing method, mak- ing the patient actively to participate. We introduct ego discharge of mouth cavity phlegmonosis to the chemotherapy sufferer, providing the patient with homologous support and help. We arouse the patient’s subjective motility. For instance, the patient had been teached the rightly method of gargles and mouth care knowledge which the patient is lacking, such as gargle immediately after vomitting. Then we make the patient understand why to do and how to do. Two patient group uses the same nursing me更多还原