【作者】 冯亚非； 李振强； 李先文；

【Author】 FENG Ya-fei LI Zhen-qiang LI Xian-wen (College of Science, Guangdong Ocean University, Zhanjiang 524088)

【机构】 广东海洋大学；

【摘要】 目的通过实验研究南海产海星中海星总皂苷的分布及最佳提取方法,并对产物进行定性分析,为源自海洋的皂苷类新药的开发提供参考。方法采用乙醇提取法和甲醇提取法从海星体内提取海星总皂苷,用显色反应、溶血实验、紫外光谱分析和薄层色谱对产物进行分析鉴定。结果干海星体壁总皂苷产率分别为0.011%和0.016%;鲜海星体壁和内脏的海星总皂苷产率分别为0.016%和0.021%。结论南海产海星中海星总皂苷主要为甾体皂苷,且结构中含有硫酸基;海星整体均有药用价值。更多还原

【Abstract】 Objective To study the abstraction and qualitative analysis of asterosaponin from starfish in Nanhai Sea. Method Asterosaponin was prepared separately by extraction with methanol or ethanol and was analysed by chromogenic reaction , hemolytic test , ultraviolet spectrum and thin layer chromatography. Result The extraction yields was 0.011% and 0.016% by methanol and ethanol. The yields of astersaponin in the body wall and internal organs was 0.016% and 0.021% respectively. Conclusion The asterosaponin was steroidal saponin , and it may be sulfuric ester steroidal saponin .更多还原