【作者】 林涛； 孙惠军； 蔡淑惠； 陈忠；

【Author】 LIN Tao SUN Hui-jun CAI Shu-hui CHEN Zhong Department of Physics,State Key Laboratory of Physical Chemistry of Solid Surface,Xiamen University,Xiamen,Fujian 361005,PR China

【机构】 厦门大学物理系,固体表面物理化学国家重点实验室；

【摘要】 <正>扩散加权成像是一种无侵害的技术,是研究脑功能和脑疾病诊断的强大工具。这一技术可以对活体中受组织结构影响的水分子布朗运动进行成像跟踪。利用远程偶极场(distant dipolar field,DDF)作用下分子运动获得扩散成像,具有与一般扩散成像不同的特性,如对运动伪影的不敏感性。本文对 DDF 扩散成像包含的独特对比度机理进行了模拟研究。结果表明 DDF 扩散成像能提供一种依赖于偶极相关距离(d_c)的全新的对比度模式。更多还原

【Abstract】 In magnetic resonance imaging(MRI),diffusion-weighted imaging(DWI)is a noninvasive technique and represents a powerful tool in the field of brain studies and brain diseases diagnosis, allowing in rive mapping the Brownian motion of water molecules that is influenced by tissue microstructures.The DWI under distant dipolar field(DDF)provides a new method with some unique properties such as low sensitivity to motion artifacts.In this report,simulations reflecting a novel contrast mechanism in DDF-DWI were carried out.The results demonstrate that DDF-DWI can provide a fundamentally different source of contrast,which depends upon dipolar correlation distance(d_c).更多还原