丽水市2004年501例药品不良反应报告分析

【作者】 何伟珍； 吴丽兰；

【机构】 浙江省丽水市中心医院；

【摘要】 目的:了解本市各医院及药品经营企业和药厂的药品不良反应报告及发生情况,探讨发生药品不良反应的因素。方法:根据2004年市药品不良反应监测中心收集的报表进行分类统计和分析评价。结果:抗感染药物引起的ADR占45．1％(226例),中药制剂16．0％(80例);ADR类型为皮肤及附件损伤最常见占48．9％(245例),其次是消化系统和循环系统损害,较严重的ADR有21 例(4．2％),从给药途径分析静脉给药引发的最多占65.9％(330例)。结论:加强专业人员的业务和服务素质培养,并进行全方位的ADR监测工作,减少和避免ADR发生。更多还原

【Abstract】 objectives: to probe ADR condition in the medicine plants and corporations in the hospitals in Lishui City and to investigate how ADR is induced. Methods: we analysed statistically the reports and forms collected by Lishui ADR Monitor Center in 2004. Results: The ratio of ADR accouted for 45. 1%(226 cases) induced by antimicrobial drugs, 16. 0%(80 cases) by Chinese traditional medicine, the other ADR was induced by the neural ,digestive systematic and circulation systematic drugs respectively ; the types of ADR included injury of the skin and accesory with most usually induced by 48. 9% (245cases), digestive system and circulation system, there were 21 cases with much more serious ADR; according to administer access, the most ADRs induced by vein administer accouted for 65. 9% (330cases), taking orally accouted for 29. 5% (148 cases). Conclusions; The factors of ADR induced include drugs , patients, apothecaries, doctors and so on , it needs to strengthen professional knowledge and service making and to monitor ADR from all aspects for reducing and avoiding ADR.更多还原