【作者】 东红升； 东贵荣； 白妍；

【Author】 DONG Hong - sheng DONG Gui - rong BAI Yan (Yueyang Hospital of Shanghai University of TCM , Shanghai 200437; Institute of Acupuncture and Moxibustion of Heilongjiang University of TCM, Harbin 150040 )

【机构】 上海中医药大学附属岳阳中西医结合医院； 黑龙江中医药大学针灸研究所；

【摘要】 目的:急性脑出血后病灶周边不同部位存在不同程度的病理生理性改变。从神经电生理学角度探讨头穴透刺对急性脑出血病灶周边不同部位神经元放电异常调节作用的机理。方法:采用自身动脉血注入法复制大鼠尾状核急性脑出血模型,应用神经细胞放电活动、甩尾反射潜伏期为观察指标,对脑出血病灶周边不同部位神经元不同时间窗放电变化进行研究。结果:模型组脑出血灶周神经元放电明显受到抑制,头穴透刺后该区域的神经元电活动明显恢复,与模型组比较差异显著(P<0．05)。结论:头穴透刺对急性脑出血病灶周边不同部位神经元放电的异常具有明显的调节作用,可促进出血灶周神经元功能的早期恢复。更多还原

【Abstract】 Objective After acute cerebral haemorrhage the neural tissue around hematoma changed physiologically and pathologically in different degree. Probe into the mechanism of acute cerebral hemorrhage treated by scalp acupuncture through researching the variation of neuron discharge in different region around the hematoma in CNS at different stage. Methods Duplicate acute cerebral haemorrhage model on wistar by means of self arterial blood injection. Take scalp penetrating puncture as therapy method. Select Pain Response Neuron Discharge Increments and Tail Flick Latency as observing norm.Results Neuron discharge of cerebral haemorrhage group was inhibited greatly. After scalp acupuncture the abnormal discharge resumed with comparision to model group (P < 0.05). Conclusion Treating acute, cerebral haemorrhage with scalp puncture therapy at early stage will have good regulation and protection on neuron discharge.更多还原