【作者】 张斌； 梁树晃； 罗斌； 邹伟波； 何韵； 廖信彪； 潘昭良；

【Author】 (~△ZHANG Bin, LIANG Shu-huang, LUO Bin, et al. /~△Faculty of Forensic Medicine, Preclinical school of, Sun Yat-sen University, Guangzhou 510080)

【机构】 中山大学基础医学院法医病理教研室； 茂南公安分局； 花都区公安局； 广东省公安厅刑科所；

【摘要】 目的探讨血清IgE在药物过敏性休克死亡鉴定中的应用价值。方法采用MEIA法,对17例明确鉴定为药物过敏性休克死亡者(休克组)和16例交通事故死亡者(对照组)的心血进行IgE检测,并对2组IgE检测结果进行统计学分析。结果休克组IgE水平为(622.49±594.67)U/ml,对照组为(45.04±43.62)U/ml;经t检验,2组显著差异(p<0.01)。结论血清IgE水平升高,可作为鉴定药物过敏性休克死亡的依据之一。更多还原

【Abstract】 Objective To study the applicability of the total serum IgE to certifying death from allergic shock induced by drugs in cadavers. Methods The levels of serum IgE were measured and analyzed statisti- cally in 17 cadavers whose cause of death had been certified as allergic shock induced by drugs and in 16 cadavers died from traffic accidents who were used as the control. Results The levels of the total serum IgE were much higher in 17 cadavers died of allergic shock induced by drugs (622.49±594.67) than those in control cases (45.04±43.62). The difference between two the groups were statistically significant (P<0.01). Conclusion The total serum IgE content in blood can be used as one of the parameters for certification of death from allergic shock when drug is suspected to be involved in the incident.更多还原