【作者】 张凡； 马向东； 余华顺； 郭永豪； 阎淳泰； 梁运祥；

【Author】 ZHANG Fan~1, MA Xiang-dong~(2, 3), YU Hua-shun~2, GUO Yong-hao~3, YAN Chun-tai~1, LIANG Yun-xiang~1(1. College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, Hubei, China; 2. Postdoctoral Programme of Hubei Angel Yeast Co,. Ltd, Yichang 443003, Hubei, China; 3. College of Biotechnology and Food Science of Henan Agricultural University, Zhengzhou 450002, Henan, China)

【机构】 华中农业大学生命科学技术学院； 湖北安琪酵母股份有限公司博士后工作站； 河南农业大学生物技术与食品科学学院；

【摘要】 当酵母菌所处环境渗透压上升的时候,酵母细胞可以通过增加胞内甘油的积累来减小细胞膜内外的渗透差以实现对高渗胁迫的适应。本文论述了酵母菌如何调控并利用合成代谢途径增加甘油合成、降低甘油通过细胞膜的速度、调控甘油的分解代谢过程和从环境中摄取甘油等4种方式来提高胞内甘油的积累。更多还原

【Abstract】 When the osmotic pressure of the environment that yeast lives enhanced, yeast would enhance intracellular accumulation of glycerol to decrease the margin between intracellular and environmental, which would help yeast adapts hyper-osmotic stress. Yeast would accumulate intracellular glycerol by four methods, which include increasing the glycerol production rate, decreasing transmembrane flux of glycerol to avoid synthesized glycerol diffuse to environment, adjusting glycerol degradative rate and uptaking glycerol from environment. This article will discuss how does yeast adjust and use the four methods to enhance intracellular accumulation of glycerol.更多还原