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老年病科铜绿假单胞菌医院感染危险因素调查

Investigation of the Nosocomial Infection Caused by Pseudomonas aeruginosa among Geriatrics Patients

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【作者】 詹毅余兰

【Author】 ZHAN Yi, YU Lan(Zhongnan Hospital, Wuhan University, Wuhan 430071, Hubei, China)

【机构】 武汉大学中南医院

【摘要】 为了探讨老年病科铜绿假单胞菌医院感染的危险因素和控制对策,对老年病科分离的铜绿假单胞菌,用常规方法进行鉴定和体外药物敏感试验。同时,收集临床资料,分析感染的危险因素,并制定相应对策。实验结果表明:138株铜绿假单胞菌主要来源于痰标本,占73.2%;对13种常用抗生素的敏感率高低不等。以阿米卡星的敏感率最高,为80.4%;感染发生的危险因素与住院时间长、患有基础疾病、切入性操作以及联合使用抗生素等有关。由此可见,铜绿假单胞菌是引起医院感染的最常见病原菌之一,对抗菌药物呈多重耐药,尤易侵袭老年患者。控制其感染的主要对策为普及全员教育。尽早控制基础疾病,注意免疫支持治疗,合理使用抗生素,认真加强消毒隔离,防止交叉感染。

【Abstract】 To study pseudomonas aeruginosa nosocomial infection among geriatrics patients, drug resistant status of 13 antibiotics was determined by K-B method, and clinical data were collected and analyzed. As result, most of strains were isolated from sputum(73.2%). Results of susceptibility test show difference among resistance rates of different antibiotics, and the sensitive rate to amicaxin is the highest(80.4%). The nosocomial infection is possibly related with time in hospital, basic disease, invasive manipulation and combinded use of antibiotics. We concluded that pseudomonas aeruginosa is one of the most common pathogens causing nosocomial infection, especially for senile patients. To control the nosocomial infection, the measurement should be taken as below: education of entire people, control of the primary disease, immunity support treatment, using antibiotics reasonably, strengthening antisepsis insulation and avoid across infection.

  • 【会议录名称】 生命科学与微生物专辑
  • 【会议时间】2004
  • 【分类号】R181.3
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