【作者】 万洪全； 刘海侠； 王书远； 吴力力； 石火英；

【Author】 WAN Hongquan, LIU Haixia, WANG Shuyuan, WU Lili, SHI Huoying (College of Animal science and Veterinary Medicine, Yangzhou University Yangzhou, 225009)

【机构】 扬州大学畜牧兽医学院；

【摘要】 用鹅副粘病毒BY株人工感染1月龄青年鸽,观察试验鸽的发病情况、临诊症状及病理变化,并对病毒抗原的组织分布进行检测,以研究鹅副粘病毒对鸽的致病性.结果表明,鹅副粘病毒人工感染可致试验鸽严重发病,发病率达100%,病死率达92%;病鸽临诊表现为下痢、眼睑发炎、呼吸困难、咳嗽,并表现瘫痪、翅膀下垂、转圈或震颤等神经症状;病理剖检和病理织织学检查表明,病鸽各种器官都存在组织损伤,但以消化系统、免疫系统和神经系统较为严重,表现显著的变性、坏死或出血等变化;免疫组化检测发现,病毒可以在病鸽体内多种组织器官中复制.本研究结果说明,鹅副粘病毒对鸽具有较强的致病性.更多还原

【Abstract】 Tweenty - six pigeons were inoculated with a paramyxovirus isolate which can naturally cause severe disease in geese, the clinical signs and histopathology were studied in an effort to determine the pathogenicity of the goose isolate for pigeons. As a result, the challenge caused 100 % morbidity and 92% morality, respectively. "Hie iefected pigeons developed clinical signs such as diarrhea, cough, ocular and nasal discharge, some of the pigeons, showed nervous signs, including tremors, ataxia, wing and leg paralysis, and torticollis. Cross lesions were found in lung, intestine, pancreas, the most conspicuous of which were congestion and edema of lung, single petechia to diffuse hemorrhage of intestinal tract, multiple necrotic foci in pancreas, while in some cases, hyperemia and hemorrhage of the brain was evident. Microscopic examination showed that most tissues of the infected birds undergone degeneration, necrosis and hemorrhage. Additionally, by using an immuno - histochemical method, the viral antigen could be detected in various tissues. The present investigation revealed that the goose - pathogenic paramyxovirus, which has caused great loss in geese in southeast China, posseses high pathogenicity for pigeons.更多还原