【作者】 张婧；

【导师】 张钊；

【作者基本信息】 河北医科大学 ， 口腔医学（专业学位）， 2022， 硕士

【摘要】 目的:探究聚多巴胺（Polydopamine,PDA）复合涂层处理对氧化锆与自粘接树脂水门汀3M ESPE Rely X^TMU200的粘接强度的影响及老化试验后粘接强度的变化。方法:1.激光切割8 mm×6 mm×2 mm氧化锆试件54个,烧结,抛光。2.将氧化锆试件随机分为3组,每组18个,进行不同的表面处理:（1）喷砂组（S组）,喷砂处理;（2）喷砂+硅烷化组（G组）,喷砂后试件表面用溶胶凝胶法制备硅涂层,并涂覆硅烷偶联剂Monobond N;（3）喷砂+PDA复合涂层组（PDA组）,喷砂后试件表面制备PDA复合涂层。3.将所有氧化锆试件与树脂块3M Z350（10 mm×8 mm×4 mm）之间行自粘接树脂水门汀3M ESPE Rely X^TMU200粘接。4.将每种表面处理组随机分为3组,分别进行以下操作:（1）自凝树脂包埋试件后在万能测试机上做粘接强度测试;（2）冷热循环组,将试件置于冷热循环仪内,以5℃和55℃水浴箱中交替浸泡30 s,间隔10 s为1次循环,循环10000次,包埋后测试粘接强度;（3）PH循环组,将试件置于37℃水浴中,人工唾液浸泡11 h和等量脱矿液浸泡1 h为1次循环,1日循环2次,循环30天,包埋后测试粘接强度。5.使用SPSS 26.0进行统计学分析,检验标准为α=0.05。结果:1.不同表面处理组,无老化处理的氧化锆与树脂之间的粘接强度:对比S组、G组和PDA组,结果显示:G组（“喷砂+硅烷化”组）的粘接强度最强,与其他两组间差异具有统计学意义（P<0.05）;PDA组（“喷砂+PDA复合涂层”组）的粘接强度值略大于S组（“喷砂”组）,但差异无统计学意义（P>0.05）。2.老化实验前后,不同表面处理组的粘接强度比较:分别对比每种表面处理在老化试验前后氧化锆与树脂之间的粘接强度,结果显示:每种表面处理经冷热循环和PH循环后,粘接强度均发生明显下降（P<0.05）。3.各表面处理组两种老化试验粘接强度的比较:“喷砂”组和“喷砂+硅烷化”组中,冷热循环和PH循环后的粘接强度相比无统计学意义（P>0.05）;“喷砂+PDA复合涂层”组冷热循环后粘接强度明显低于PH循环后,有统计学意义（P<0.05）。4.不同表面处理组老化试验后粘接强度“下降率”的比较:将不同表面处理组老化试验后粘接强度的下降率进行比较,结果显示:“喷砂+PD A复合涂层”组冷热循环和PH循环老化后粘接强度下降率最多,明显高于其他两组,具有统计学意义（P<0.05）,“喷砂+硅烷化”组下降率稍高于“喷砂”组,无统计学意义（P>0.05）。结论:1.硅烷化后氧化锆与树脂之间粘接强度最强;PDA复合涂层处理后的粘接强度略有增加。2.老化实验后,每个表面处理组的氧化锆与树脂的粘接强度均下降。PDA组粘接强度下降率最大,硅烷化组下降率稍高。3.老化试验后,硅烷化组经冷热循环老化与经PH老化后的粘接强度值相近,PDA组经冷热循环老化后粘接强度值明显小于PH老化后。更多还原

【Abstract】 Objective:To explore the effect of polydopamine（PDA）composite coating on the bonding strength of zirconia and resin adhesive 3M ESPE Rely X^TMU200 and the change of bonding strength after aging test.Methods:1.54 zirconia specimens of 8 mm×6 mm×2 mm were made,sintered,polished and sandblasted.2.We divided the zirconia specimens into three surface treatment groups randomly with 18 specimens in each group:（1）Group S（Sandblasting group）,sandblasting zirconia;（2）Group G（Sandblasting+silanization group）,after sandblasting,silica coating was prepared by sol-gel method and silane coupling agent Monobond N was coated;（3）Group PDA（Sandblasting+PDA composite coating group）,after sandblasting,PDA composite coating was fabricated on the surface of specimens.3.All zirconia test pieces and resin blocks 3M Z350（10 mm×8 mm×4mm）were bonded by self-bonding resin cement 3M ESPE Rely X^TMU200.4.Each surface treatment group was randomly divided into three groups to do the following operation individually:（1）Shear strength test was performed on a universal testing machine after embedding test specimens with self-setting resin;（2）Thermocycling group,the specimens were placed in the thermocycling instrument and soaked alternately in 5℃and 55℃water bath for 30 s,with an interval of 10 s for a cycle of 10000 times,and the shear strength was tested after embedding;（3）PH cycle group,the specimens were placed in a 37℃water bath,immersed in artificial saliva for 11 h and equal amount of demineralization solution for 1 h.The above process was used as a cycle,twice a day for 30 days.Then the shear strength was tested after embedding specimens.5.Statistical analysis was performed using SPSS 26.0,and the test standard wasα=0.05.Results:1.Bonding strength between zirconia and resin in different surface treatment groups without aging treatment:compared with Group S,G and PDA,the results showed that the bonding strength of Group G was the strongest,and the difference was statistically significant（P<0.05）;The bonding strength of Group PDA was slightly higher than that of Group S,but there was no significant between the bonding strength of two groups（P>0.05）.2.Comparison of bonding strength of different surface treatment groups before and after the aging test:the bonding strength between zirconia and resin of each surface treatment was compared before and after the aging test.The results showed that the bonding strength of each surface treatment decreased significantly after Thermocycling and PH cycle（P<0.05）.3.Comparison of bonding strength between two aging tests in each surface treatment group:in Group S and Group G,there was no statistical significance in the bonding strength after thermocycling and PH cycle（P>0.05）;The bonding strength of Group PDA after thermocycling was lower than that after PH cycle,with statistical significance（P<0.05）.4.Comparison of"decrease rates"of bonding strength in different surface treatment groups after aging tests:The decrease rates of bonding strength in different surface treatment groups after two aging tests were compared,and the results showed that:The bonding strength of Group PDA decreased the most after thermocycling and PH cycle,which was higher than that of others,with statistical significance（P<0.05）.The bonding strength of Group G decreased slightly higher than that of Group S,with no statistical significance（P>0.05）.Conclusions:1.After silanization,the bonding strength between zirconia and resin was the strongest,which was statistically significant;The bonding strength of PDA composite coating increased slightly,but the difference was not statistically significant.2.After the aging test,the bonding strength of zirconia to resin in each surface treatment group decreased,with statistical significance.The decrease rate of bonding strength was the largest in the PDA group,which was statistically significant,and the decrease rate was slightly higher in the silanization group,but the difference was not statistically significant.3.After thermocycling,the bonding strength of Group G was similar to that after PH cycle,and the change value of bonding strength of Group PDA was significantly smaller than that after PH cycling.更多还原