【作者】 王富民；

【导师】 颜国正；

【作者基本信息】 上海交通大学 ， 精密仪器及机械， 2008， 硕士

【摘要】 目前推进式內窥镜的检查方式?崛孟兰膊』颊吒芯醪皇省S?其针对小肠出血性疾病的诊断,推进式内窥镜难以到达,即便能够到达,在插入过程中也会引起极大的痛苦。许多患者因为恐惧而放弃检查,最终导致严重后果。胶囊内窥镜通过患者口服的方式,安全而无痛苦地通过人体消化道,拍摄沿途数万张影像,基本解决小肠病变检查难的问题。胶囊内窥镜是实现对消化道疾病诊断的全新医疗仪器,优点是:诊断过程对人体组织几乎无损伤,可反复观察;患者无痛苦,可以自由行动;可获得人体消化道内壁的数字化图像,便于处理和存储,通过患者数据库、样本库的建立,利于多个病例的比较诊断;真实反映人体消化道特别是小肠等不易观察到的器官情况,诊断快捷准确。由于胶囊内窥镜的上述特点及其在临床应用方面的优势,得到了国际生物医学工程领域的高度重视。本文以国家自然科学基金资助项目(项目编号:30570485)和国家高技术研究发展计划(863计划)资助项目(项目编号:2006AA04Z368)为依托,提出了一种结构简单、造价低廉的胶囊内窥镜系统总体方案;针对目前国内外的胶囊内窥镜电子系统装置中附加设备过多的弊端,提出了集成化、精简化的胶囊内窥镜电子系统设计思路,设计制作了胶囊内窥镜系统的摄像模块、无线收发模块和体外数据存储模块;基于临床应用要求,在实现对人体消化道内壁的数字化图像实时获取和传输的同时,着重考虑了系统软硬件设计,以降低系统的成本与功耗,延长连续工作时间,并且可以方便调整输出图像帧速;完成了胶囊内窥镜样机的研制,实现了对获得的人体消化道内壁图像数据的实时传输及在大容量CF卡中的存储。系统结构简单,为进一步的研究和临床应用打下了坚实的基础。更多还原

【Abstract】 Traditional application of push-endoscope on medical diagnosis is invasive. Especially for the diagnosis of small intestine bleeding diseases, push-endoscope is unreachable. Many patients choose to give up the diagnosis, which often leads to serious aftermath.Wireless Capsule Endoscope(WCE) is a newly-developed non-invasive measurement of alimentary canal diagnosis, which could pass through human body with thousands of image shots, while causing no damage. The invention generally solves the problems exsiting in the small intestine dignosis. The system’s prominent merits are listed as follows. 1) The process of dignosis is invasive, with good repeatability. 2) No painfulness. Patient could move freely. 3) Accessible to the digital images of human alimentary canal, which is easy for storage and compression and comparable to various cases through the patients database.4) Direct image acquisition of unobservable organs, improves the dignosis accuracy. Due to the advantages listed above, WCE related projects draw the attention from international biomedical fields.The thesis, sponsered by National Natural Science Fund Program (No. 30570485) and National Hi-Tech Development Project (863 Project), introduced a simple structured WCE solution with low cost. The system, based on an integration and simplicity-centered scheme, consists of camera module, radio frequency module and In Vitro data storage module. In terms of the clinical requirement, we reconsidered the design of software and hardware while realizing the function of real-time image acquisition and transmission in order to lower the power consumption. The new developed prototype device could also easily adjust the frame rates by modification on software and hardware. Moreover, the image data transmitted could be received and stored on a CF card based system. The simplification of structure paves the way for further research as well as clinical application.更多还原