【作者】 王丹；

【导师】 吕景文；

【作者基本信息】 长春理工大学 ， 材料物理与化学， 2011， 硕士

【摘要】 随着生活水平的日趋提高,人们对生物活性材料应用到生活中的要求也越来越迫切。本文研究了一种具有良好生物相容性,且其它物理化学性质均适宜人体应用的生物活性材料。它不仅对人体组织无害,还能够促进组织的修复再生。采用高温熔融法,通过一次烧制,制得生物活性玻璃陶瓷。利用XRD、SEM等先进测试技术对该生物活性玻璃陶瓷进行了测试研究,结果表明：该生物活性玻璃陶瓷主晶相为羟基磷酸钙,具备良好的生物相容性,且颗粒圆润均匀,引入的Ag+离子和Zn2+离子增强了该生物活性玻璃陶瓷对口腔细菌的抑制作用和杀菌作用。引入Sr2+提高了该生物活性玻璃陶瓷的硬度。羟基磷酸钙是人体骨骼的主要组成成分,本文制备的主晶相为羟基磷酸钙的生物活性玻璃陶瓷,综合了玻璃和陶瓷的优点,是一种理想的生物活性材料。在国内外还未见此研究的报道,本成果已经申请国家发明专利,为科学工作者进一步开发先进的生物活性玻璃陶瓷材料奠定了坚实的基础。更多还原

【Abstract】 More urgent requirement that bioactive materials can be applied to human living activities has been brought about with the enhancement of living standard. In this work, a sort of bioactive material with excellent biocompatibility was investigated, which is suitable for human-body application based on its properties of physics and chemistry. This material not only has no harm to human body but also can promote renewable repairing of human organization.The preparation of bioactive macor was achieved by high temperature melting method with once sintering, and it was investigated through advanced measurement techniques, such as XRD, SEM, etc. Experimental results show that the principal crystalline phase of this bioactive macor belongs to hydroxyl calcium phosphate, which has excellent biocompatibility and uniform round particles. The introduction of the Zn2+and Ag+ions enhances the effect of bioactive macor on the inhibition of oral bacteria and sterilization. Meanwhile, the introduced Sr2+ ion improves the hardness to the bioactive macor. As the main components of human body skeleton, the prepared bioactive macor with hydroxyl calcium phosphate as its principal crystalline phase is an ideal bioactive material. It has the advantages of both glass and ceramic. No research reports as the same have been seen at home and abroad. The achievement in this work has been applied for the national patent of invention, which has laid a solid foundation for further development of bioactive macor material.更多还原