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Ⅱ期原发性肝癌(HCC)的中医证候特点研究

【作者】 杨昆蓉

【导师】 叶永安;

【作者基本信息】 北京中医药大学 , 中医内科学, 2011, 硕士

【摘要】 研究背景:近年来中医药治疗肝癌的研究取得了较大的进展。中医药治疗肝癌具有缓解临床症状,改善生存质量,延长生存期及配合放化疗减毒增效等作用。尤其对于Ⅱ期肝癌来说,随着肝动脉化疗栓塞术(TACE)的普及,配合中医药治疗,给患者的生存带来更大的希望。研究Ⅱ期肝癌的中医证候规律特点,具有现实意义和临床价值。肝癌的中医病因病机复杂,中医证候辨证分型目前尚缺乏公认统一标准。目的:为规范肝癌的中医辨证分型提供参考,更好的指导临床诊治,提高临床疗效。方法:采用横断面调查方法,收集和分析80例Ⅱ期肝癌症状出现频率明确Ⅱ期肝癌的证候分布及特点结果:40岁以上的HBV感染人群为肝癌高发人群;Ⅱ期HCC中医证候以复合证候多见(占71.2%),单一证候偏少(占28.8%);复合证候中气滞证+血瘀证最多见,其次是气滞证+脾虚证及脾虚证+血瘀证;Ⅱ期HCC中医证候特点以气滞血瘀,脾虚气滞为常见;湿热证及阴虚证在Ⅱ期HCC中较少见结论:Ⅱ期原发性肝癌中医证候中以气滞证+血瘀证最多见,其次是气滞证+脾虚证及脾虚证+血瘀证。

【Abstract】 Background:Chinese medicine in the treatment of liver cancer research have ach-ieved considerable progress in recent years.TCM therapy for liver cancer has all-eviate clinical symptom, and improve the living quality and prolong surial and cooperate with chemoradiation minus poison efficiency functions.Ⅱ-term of pri-mary liver cancer patients with liver arterial chemoembolization and traditional Chinese medicine therapy has better curative effect. ResearchingⅡ-term of TCM syndrome of primary liver cancer regulation characteristics, has practical signi-ficance and clinical value. TCM etiology and pathogenesis of HCC are complex, the syndromes typification is still lack of recognized unified.Objective:The goal of this research is to provide primary liver cancer syndrome differentiations reference,and provide reference for clinical diagnosis and treat-ment of better guidance, improve the clinical effect.Methods:Through cross-sectional survey methods,we collect and analysisⅡ-term 80 cases of primary liver cancer symptoms, in order to make clear the frequency distribution and features primary liver cancer syndrome.Results:People over the age of 40 with HBV infection were high-risk groups for HCC; Composite syndromes are common syndromes of theⅡ-term of primary liver cancer (accounted for 71.2%); Single syndromes are rare (accounted for 28.8%); The most common composite syndromes of theⅡ-term of primary liver cancer are qi stagnation syndrome plus blood stasis syndrome,the second are qi stagnation syndrome plus spleen deficiency syndrome and spleen deficiency syn-drome plus blood stasis syndrome; The syndrome features of theⅡ-term of pri-mary liver cancer are qi and blood stasis, deficiency of the spleen and qi stagna tion. Damp-heat syndrome and yin deficiency syndrome are rare in this period.Conclusion:The common syndromes of theⅡ-term of primary liver cancer are qi stagnation syndrome plus blood stasis syndrome,the second are qi stagnation syndrome plus spleen deficiency syndrome and spleen deficiency syndrome plus blood stasis syndrome.

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