【作者】 崔清风；

【导师】 吴仁毅；

【作者基本信息】 浙江大学 ， 临床医学， 2010， 硕士

【摘要】 目的：分析青光眼住院手术患者的内部构成比及其性别、年龄分布,为青光眼的防治研究提供流行病学参考。方法：回顾分析浙江大学医学院附属第二医院眼科2001年1月～2008年12月期间青光眼住院手术患者资料,共1983例(1983眼),按术后诊断分为：急性原发性闭角型青光眼(PACG)、慢性PACG、原发性开角型青光眼(POAG)、继发性青光眼(SG)和先天性青光眼(CG)。统计住院手术患者的年龄、性别分布及各种类型青光眼的构成比,分析其内部构成比及变化趋势。将原发性青光眼患者按年龄分为6个时间组(<40,40-50,50-60,60-70,70-80和>80岁),观察不同性别组患者人数的分布情况。结果：8年间原发性青光眼、SG和CG各占青光眼总数的61.82%、31.01%和7.16%。住院手术患者中,PACG患者男：女=1：2.05；POAG患者男：女=2.41：1；SG患者男：女=1.94：1；CG患者男：女=1.45：1。原发性青光眼住院手术患者中,PACG,患者男性和女性均多见于60-70岁年龄组。POAG患者女性多见于50-60岁年龄组(31.7%),而男性多见于40-50岁年龄组(21.7%)。40岁以下原发性青光眼手术患者以POAG患者多于PACG,而40岁以上则相反。结论：本研究表明原发性青光眼尤其是PACG是青光眼住院手术患者的主要类型。40岁以上人群中,PACG可能是青光眼防治的重点,而40岁以下人群的防治重点则可能是POAG。更多还原

【Abstract】 Objective: To analyse the proportions of each glaucoma subtype, gender and age of glaucoma inpatients admitted for surgeries.Methods:Data of glaucoma inpatients admitted in the Eye Center of the 2nd Affiliated Hospital, Medical College of Zhejiang University from January 2001 to December 2008 were reviewed and analysed. The proportions of different glaucoma subtypes [acute primary angle-closure glaucoma (aPACG), chronic primary angle-closure glaucoma (cPACG), primary open angle glaucoma (POAG), secondary glaucoma (SG) and congenital glaucoma (CG)], age groups (<40,40-50,50-60,60-70,70-80, and>80 years), and gender of the patients undergone anti-glaucoma surgeries were calculated. The trends of proportions from 2001 to 2008 were also analysed.Results: A total of 1983 glaucoma patients were included for the analysis, of which the proportions of primary glaucoma, SG and CG were 61.82%,31.07% and 7.16%, respectively. The gender ratios (male:female) of PACG, POAG, SG and CG were 1:2.05,2.41:1,1.94:land 1.45:1, respectively. For PACG, the highest proportions of male and female patients were found to have an age of 60-70 years, while for POAG, higher proportion of patients were seen in the age group of 40-50 years for men and 50-60 years for women. There were more POAG patients than PACG patients with an age<40 years, while in patients>40 years PACG were more seen than POAG.Conclusions:Patients of primary glaucoma, especially PACG, were the major glaucoma population admitted for surgeries in aforementioned Eye Center from 2001-2008. Our results suggest that PACG might be important in persons> 40 years, while POAG in persons< 40 years, in terms of glaucoma prophylaxis and treatment.更多还原