【作者】 杨丽蓉；

【导师】 傅晓晴；

【作者基本信息】 福建中医学院 ， 中医诊断学， 2006， 硕士

【摘要】 本文从理论和流行病学研究两方面，深入探讨围绝经期妇女证素特点和证素存在的病理基础，有助于进一步完善中医围绝经期病理理论，弥补围绝经期前证的辨证诊断和治疗缺乏客观化和规范化的不足，为临床围绝经期妇女预防保健治疗提供基础研究和新思路。 理论研究部分对女性中医生理病理理论进行了疏理，对围绝经期妇女的生理病理特点从理论上进行了发掘和整理。认为：女子以肝为先天，肝是气血调节之枢，女子生理以肝为主导，亦与肾有密切关系。肾藏元阴元阳，调节全身阴阳。病理上，肝肾虚损为围绝经期发病的根本原因，肝郁为本期病理的基本环节，是本期发病的病理基础之一。 临床研究部分选择300例非显病体检妇女，通过对围绝经期妇女流行病学的临床研究及各项指标的观测，得出以下结论： (1) 围绝经期妇女存在不同程度的病理变化，肝肾为围绝经期妇女的主要病位，阴虚是围绝经期妇女的主要病性证素。 (2) 证素积分可以为潜证的诊断提供基础。 (3) 围绝经期妇女中医证素和西医客观指标之间存在相关性，甘油三脂(TG)与痰湿、气滞相关；BUN／CREA与阴虚相关；高密度脂蛋白(HDL-C)与气滞相关。血液生化可能是证素存在的生化基础；血液生化水平与相关证素的病理变化不呈对应关系。 通过研究，从流行病学角度初步探讨了围绝经期妇女证素分布的特点，从现代医学血液生化角度初步探讨了围绝经期证素存在的病理基础，应用辩证积分方法进行辨证，为降低围绝经期综合征发生率，治疗围绝经期综合征以及对围绝经期妇女预防保健提供基础研究。同时对本课题存在的不足之处进行了讨论分析。更多还原

【Abstract】 In this paper the feature of symptom-complex Amoxcillin and their existing patho-fundament in perimenopausal period were studied through theoretical and clinical researches, which were helpful to perfect the TCM theory of reproductive physiology and pathology, to make up insufficiency in peri-menopausal period pro-symptom-complex differentiation of symptoms and signs diagnosis and reatment which be short of objective and normalization, and also provided a basic research and a new idea for the prevention , health protection and treatment of perimenopausal period.In the theory research section ,the TCM theory of reproductive physiology was cleared up and that of etiological factor and mechanism of perimenopausal period was studied.Liver was innateness for female. Liver was center of QI-blood adjustment.it is conducted mostly by liver and intimate with kidney for female physiology. There were renal yin and renal yang in kidney which adjust yin-yang of all over the body.on pathology, liver and renal deficiency was basic reason, stagnation of liver-QI was basic component element and one of patho-base.In the clinical research section, 300 unapparent-illness medical examination female cases were observed , through epidemiological clinical research and every item index observation, the result showed that:(1) The peri-menopausal period female have different degree pathological change , Liver and kidney were significant disease position in peri-menopausal period femme, yin asthenia was main disease character for peri-menopausal period female .(2) Symptom-complex Amoxcillin integral calculus may provide foundation for latent symptom-complex diagnosis.(3) There were dependability between TCM syndrome Amoxcillin and objective index in in perimenopausal period, for instance, between TG and phlegmatic hygrosis and Qi更多还原