【作者】 臧国尧；

【导师】 王义荣；

【作者基本信息】 浙江大学 ， 神经外科， 2006， 硕士

【摘要】 目的 评价动态脑电图、体感诱发电位、脑干听觉诱发电位三种神经电生理检查在昏迷患者预后判断中的作用。 材料和方法 前瞻性对32例生命体征稳定的昏迷病人进行动态脑电图、体感诱发电位、脑干听觉诱发电位检查来预测其一周清醒率。动态脑电图按国内黄远桂标准进行诊断;体感诱发电位记录N9、P15、N20、P25波;脑干听觉诱发电位记录Ⅰ、Ⅲ、Ⅴ波,分析诱发电位各波潜伏期、峰间期及双侧波幅差异。对各组患者昏迷期测得数据先进行单因素方差分析。其中对计量资料采用独立样本t检验,对计数资料采用x~2检验。对单因素分析p<0.05的因子进行更多还原

【Abstract】 ObjectiveTo evaluate the value of electroencephalogram and short latency somatosensory evoked potentials and auditory evoked potentials in prediction of the outcome in comatose patients.MethodsElectroencephalogram and short latency somatosensory evoked potentials and auditory evoked potentials wereexamined in 32 comatose patients. The electroencephalogram result was diagnosed by HuangYunGui’s standard. The short latency somatosensory evoked potentials were recorded N9、 P15、 N20、 P25, and the auditory evoked potential were recorded Ⅰ、Ⅲ、Ⅴ. One way ANOVA analysis was used to the data about the comatose stage. And independent t test was used to an uncounted data and x test was used to an counted data. Then logistic regression analysis was used .Results(P25-N20) IPL and (Ⅲ-Ⅴ)IPL were an important influencing factors come to short-term and predicted to the pathients with coma. The OD of prolonged (P25-N20) IPL and (Ⅲ-Ⅴ )IPL>2 were 2.318 (p=0.02 ) and 0.112 (p=0.036 ), and the positive predicted probability was 87.5% and the negative predicted probability was 81.3%. Electroencephalogram, P25 IPL、 V IPL and ( Ⅰ-Ⅴ)IPL might be an influencing factors come to short-term and predicted to the pathients with coma too, but unreached statistics significance.Conclusion(P25-N20) IPL and (III-V)IPL were an important influencing factors come to short-term and predicted to the pathients with coma.更多还原