【作者】 陈立翰；

【导师】 刘爱伦；

【作者基本信息】 浙江大学 ， 基础心理学， 2005， 硕士

【摘要】 本研究采用不同性质的视觉刺激(图形和文字),结合行为反应和事件相关电位(ERP)技术,通过考察在简单规则抑制(nogo)和复杂规则抑制(3个连续计数nogo和5个连续计数nogo)不同加工条件下抑制的差异,研究基于规则记忆的Go/Nogo任务中,不同的加工水平的抑制现象和揭示记忆抑制的神经基础,并从认知神经科学方面考察工作记忆的中央执行的抑制功能和验证情景缓冲器的假设。实验结果显示:在不同性质的视觉Nogo刺激下,行为数据的反应时间、Nogo-N2的潜伏期或反应电势的振幅有各自的差异;而Nogo—P3反应电势振幅均有显著性的差异,并推论出这些差异可能与不同的抑制加工深度有关。研究对中央执行系统在刺激特征联合的反应抑制中的功能和由Baddeley(2000)新工作记忆模型中提出的情景缓冲器假设进行了验证。同时也从事件相关电位(ERP)技术的角度对工作记忆加工单元的容量以及记忆编码和提取抑制的大脑两半球的不对称模型进行了验证。 本研究获得了以下结论: (1)在nogo抑制条件下,N2和P3波是特征的抑制波,但P3的波幅是反应抑制加工深度的良好指标; (2)对刺激的顺序编码加工的ERP验证了工作记忆的处理单元的容量为4左右; (3)在Go/nogo序列反应中,编码加工体现为右脑优势,而抑制提取的加工负波集中在左脑前额和前角回区(ACC)。 (4)研究揭示了中央执行系统在刺激特征联合的反应抑制中的功能,支持由Baddeley(2000)新工作记忆模型中提出的情景缓冲器的假设。更多还原

【Abstract】 To investigate the inhibition functioning of the Central Executive, Rule-based Memory inhibition ERP study is a main approach in cognitive neuroscience. Two experiments were conducted continuously via go/nogo paradigm. Two kinds of stimuli are presented in two processing conditions: one is simple inhibition(nogo),the other is complex inhibition(counting3 nogo and counting5 nogo).The purpose of the study is to unravel the relationship between N2 and P3 under new working memory model proposed by Baddeley(2000).Meanwhile,the visual working memory capacity and HERA model are also validated in the study. The main findings of the study are as follows:(1) Both N2 and P3 are the characteristic ERPs under nogo inhibition,but P3 amplitude is a good indicator of inhibition processing depth;(2) Through ERP waveforms separation from encoding of stimuli sequence,we verify that the capacity of visual working memory is about 4 units;(3) In the go/nogo sequence response, encoding is mainly the function of right hemisphere, but inhibition retrieval is concentrated on left frontal area and anterior cingulated cortex(ACC).(4) Central Executive plays a key role in response inhibition,episodic buffer proposed in Baddeley new working memory model is where the feature binding happens.更多还原