【作者】 唐彦慧；

【导师】 谭少健；

【作者基本信息】 广西医科大学 ， 眼科学， 2005， 硕士

【摘要】 目的:比较多焦点人工晶状体(MIOL)与单焦点人工晶状体(SIOL)术后远期视力、对比敏感度和视觉现象,以评价多焦点人工晶状体的有效性和安全性。方法:研究组为在我院行白内障超声乳化吸除联合植入多焦点人工晶状体AMO Array SA-40N 手术的病人33 例50 眼,对照组为植入单焦点人工晶状体AMO SI40NB 的病人28 例43 眼,随访时间均为术后6 个月以上,平均随访时间研究组为18.26±10.16 月,对照组为20.56±12.30 月。分别检查非矫正远视力、最佳矫正远视力、非矫正近视力、最佳矫正近视力、矫正远视度数下的近视力,以及矫正近视力下的对比敏感度,问卷调查视物情况及视觉症状。结果:研究组的非矫正远视力、矫正远视力和矫正近视力与对照组没有显著性差异。MIOL 组有41 眼(82.00%)非矫正近视力0.5 以上,SIOL 组仅有6 眼(13.95%)非矫正近视力0.5 以上,差异有显著性(P<0.05)。MIOL组矫正远视度数下的近视力好于对照组,MIOL 组有46 眼(92.00%)达到0.5以上,SIOL 组仅有13 眼(30.23%)达到0.5 以上,差异具有显著性(P<0.05)。两组病例的对比敏感度值位于正常值范围,研究组和对照组总体的对比敏感度值在各频率段没有差异。将对比敏感度值分为视力<1.0 组与视力≥1.0 以上组进行比较时,MIOL 在6.0CPD、12CPD、18CPD 时前者的对比敏感度值较后者降低,有显著性差异(P<0.05)。SIOL 仅18CPD 的差异有显著性。将对比敏感度值按照散光分为≥0.5D 组<0.50D 与进行比较时,研究组在3.0CPD、6.0CPD、12CPD、18CPD 时前者较后者下降,统计学上有显著性差异(P<0.05)。对照组仅在18CPD 时受影响。研究组有5 例6 眼术后有光晕现象,但没有影响到日常的生活。对照组有1 例1 眼出现类似的视觉现象。结论:植入多焦点人工晶状体的病人术后远期可以获得比单焦点人工晶状体好的近视力,而远视力正常。近对比敏感度值正常,但易受散光和最佳矫正近视力的影响。患者都较少出现光晕等视觉现象。多焦点人工晶状体是有效而安全的人工晶状体。更多还原

【Abstract】 Objective: Comparing the long term visual acuity,contrast sensitivity and visual symptoms of the multifocal intraocular lenses (MIOL) eyes with monofocal intraocular lenses (SIOL)eyes to evaluate the safety and effectiveness of the MIOL. Methods: 33 cases 50 eyes of MIOL implantation were enrolled at investigational sites. 28 cases 43 eyes of SIOL implantation were enrolled in a control substudy.All the cases were performed the cataract phacoemusification and intraocular lenses implantation surgery.All the patients were more than 6 months post operation.Average times was 18.26±10.16 months in investigational sites and 20.56±12.30 months in control sites.Patients were examined at random about uncorrected distant visual acuty,best corrected distant visual acuty,uncorrected near visual acuty,best corrected near visual acuty, distance corrected near visual acuty, contrast sensitivity in the near-corrected,and visual symptoms were observed by questionnaire. Results: There was no significant difference about uncorrected distant vision, best corrected distant vision and best corrected near vision between two groups. There were 41 eyes(82.00%)in MIOL group have uncorrected near vision better than 0.5,and control group only have 6 eyes (13.95%),difference has significance(P<0.05). MIOL group has better distance corrected near visual acuty than control group.MIOL group have 46 eyes(92.00%)better than 0.5,and SIOL group only have 13 eyes(30.23%),difference has Significance.Contrast sensitivity in the two groups were in the normal range, and did not differ from each other. The contrast sensitivity of vision worser than 1.0 was lower than that’s of the vision better than 1.0,and there is statistics significance in 6.0CPD、12CPD、18CPD in the MIOL group,and 18CPD in the control group. In the study group, when astigmatism was 0.5 diopters or more, contrast sensitivity was worse than that’s astigmatism not reach to 0.5 diopiters in 3.0CPD、6.0CPD、12CPD、18CPD.In the control group,astigmatism has influence on the contrast sensitivity only in 18 CPD. Five cases 6 eyes of investigational sites and 1 case 1 eye of control group reported Halo,but the majority not being bothered by these at all. Conclusion:MIOL has better near visual acuity than SIOL group,and distance visual acuity in gear.Long term contrast sensitivity of MIOL implantation was in the normal rage,but easy to be influenced by astigmatism and best corrected near vision.MIOL is safety and effectiveness.更多还原