【摘要】 为研究艾灸、白针、电针和激光照射肾俞穴（BL-23）对兔肾主动脉血流动力学的影响。本试验将30只无特定病原体（SPF）级新西兰大白兔随机分为艾灸组、白针组、电针组、激光组和空白对照组，每组6只。试验组分别通过艾灸、白针、电针和激光照射刺激肾俞穴，并于刺激前、刺激15、30、45、50 min、停止刺激10 min时，通过红外热成像仪检测穴位表面温度，通过超声多普勒检测肾主动脉血流动力学参数，并分析穴位表面温度与肾主动脉血流动力学参数的相关性。结果显示，与刺激前相比，艾灸组刺激时（P<0.01）和刺激后（P<0.05）试验兔穴位表面温度显著升高；与空白对照组相比，艾灸、白针、电针和激光照射BL-23均可使肾主动脉收缩期峰值流速（PSV）和舒张末期流速（EDV）升高，阻力指数（RI）和搏动指数（PI）降低，血管直径和血流量显著增加（刺激30、45、50 min和停止刺激10 min,P<0.05或P<0.01）。相关性分析结果显示，BL-23穴位表面温度与肾主动脉时间平均峰值速度（R~2=0.35,P<0.05）、血管直径（R~2=0.76,P<0.01）、血流量（R~2=0.65,P<0.01）均呈正相关。结果表明，艾灸、白针、电针和激光照射BL-23均可有效改善肾血流动力学和血液循环。本试验结果为针灸治疗动物肾脏疾病提供了理论依据。更多还原

【Abstract】 This study aimed to investigate the effects of moxibustion, acupuncture, electroacupuncture, and laser irradiation at the Shenshu acupoint(BL-23) on renal artery hemodynamics in rabbits. Thirty specific pathogen-free(SPF) New Zealand White rabbits were randomly assigned to five groups(n = 6 per group): moxibustion, acupuncture, electroacupuncture, laser irradiation, and blank control. In the treatment groups, BL-23 was stimulated by the respective interventions. Acupoint surface temperature and renal artery hemodynamic parameters were measured before stimulation, at 15, 30, 45, and 50 min during stimulation, and 10 min after cessation stimulation using infrared thermography and Doppler ultrasonography, respectively. Correlations between acupoint surface temperature and renal artery hemodynamic parameters were analyzed. The results showed that, compared with before stimulation, acupoint surface temperature in the Moxibustion group increased significantly during stimulation(P < 0. 01) and after stimulation(P < 0. 05). Compared with the Blank control group, moxibustion, acupuncture, electroacupuncture, and laser irradiation at BL-23 all increased peak systolic velocity(PSV) and end-diastolic velocity(EDV), decreased the resistance index(RI) and pulsatility index(PI), and significantly increased vessel diameter and blood flow(at 30, 45, and 50 min during stimulation and 10 min after cessation stimulation, P < 0. 05 or P < 0. 01). Correlation analysis revealed that BL-23 acupoint surface temperature was positively correlated with time-averaged peak velocity(R~2 = 0. 35, P < 0. 05), vessel diameter(R~2 = 0. 76, P < 0. 01), and blood flow(R~2 = 0. 65, P < 0. 01) of the renal artery. These findings indicate that moxibustion, acupuncture, electroacupuncture, and laser irradiation at BL-23 can effectively improve renal hemodynamics and blood circulation. This study provides a theoretical basis for the application of acupuncture-based therapies in the treatment of renal diseases in animals.更多还原