【摘要】 猪瘟病毒(classical swine fever virus, CSFV)是引发猪瘟(classical swine fever, CSF)的病原体。CSF对养猪业造成严重影响，感染猪可出现严重临床症状甚至死亡，显著降低猪群存活率、生长性能及经济效益。深入解析CSFV的致病机制是有效防控该病的关键基础。近年来，关于CSFV感染后宿主信号通路变化的研究日益增多，为揭示其致病机制提供了新视角。综述CSFV感染诱导的宿主信号通路变化，深入探讨这些变化在病毒致病过程中的作用，不仅有助于深化对CSFV与宿主互作机制的理解，也可能为完善CSF防控策略及抗病毒研究提供重要的理论基础和科学依据。更多还原

【Abstract】 Classical swine fever virus(CSFV) is the causative agent of classical swine fever(CSF).The disease has a serious impact on the pig industry.Infected pigs can have serious clinical symptoms or even die, which significantly reduces the survival rate, growth performance, and economic benefits of pigs.In-depth analysis of the pathogenic mechanism of CSFV is the key basis for effective prevention and control of the disease.In recent years, there have been increasing studies on changes in host signaling pathways after CSFV infection, which provide a new perspective for revealing its pathogenic mechanism.This article aims to review the changes in host signaling pathways induced by CSFV infection and to explore the role of these changes in the pathogenesis of the virus.This review not only helps to deepen the understanding of the interaction mechanism between CSFV and its host, but also may provide an important theoretical basis for improving CSF prevention and control strategies and antiviral research.更多还原