【摘要】 依达拉奉作为一种抗氧化剂，用于治疗缺血性脑卒中和肌萎缩侧索硬化。其主要作用机制为清除氧自由基、降低氧化应激水平。此外，依达拉奉还被认为具有抗炎及抗凋亡等作用。鉴于具有复杂病理机制的神经系统疾病、心血管系统疾病以及化疗药物所致的损害均在不同程度上与氧化应激损伤相关，依达拉奉被认为是一种具有广阔应用前景的药物。当前，依达拉奉的研究焦点主要集中在新型制剂的开发和联合用药策略等方面。随着对其作用靶点和作用机制的深入探索，其适应证有望进一步拓展。更多还原

【Abstract】 Edaravone acts as an antioxidant for ischemic stroke and amyotrophic lateral sclerosis.Its main mechanism is to scavenge oxygen free radicals and reduce oxidative stress levels.In addition,edaravone also has anti-inflammatory and anti-apoptotic effects.Given that neurological diseases with complex pathological mechanisms,cardiovascular system diseases,and damage caused by chemotherapy drugs are all associated with oxidative stress damage to varying degrees,edaravone is considered a drug with broad application prospects.At present,the research of edaravone mainly focuses on the development of new formulations and combination drug strategies.With the in-depth exploration of its targets and mechanism,indications of edaravone are expected to be further explored.更多还原