【摘要】 目的 探究个体化肠内营养支持结合加速康复外科（enhanced recovery after surgery, ERAS）在喉癌合并2型糖尿病（type 2 diabetes mellitus, T2DM）患者中应用效果。方法 选择2022年10月—2024年10月在福建医科大学肿瘤临床医学院（福建省肿瘤医院）治疗的102例喉癌合并T2DM患者，根据护理方法不同分为对照组（常规护理）及研究组（个体化肠内营养支持结合ERAS）各51例，对比两组围手术期指标、血糖水平、营养状态评分及并发症。结果 研究组护理满意度评分高于对照组，差异有统计学意义（P<0.05）。术后3 d、7 d、14 d、1个月，研究组疼痛评分均低于对照组，差异均有统计学意义（P均<0.05）。护理后，研究组空腹血糖、餐后2 h血糖水平均低于对照组，差异均有统计学意义（P均<0.05）。护理后，研究组主观整体营养评估表评分低于对照组，差异有统计学意义（P<0.05）。两组并发症发生率比较，差异无统计学意义（P>0.05）。结论 喉癌合并患者接受个体化肠内营养支持结合ERAS干预，可减轻术后疼痛，降低血糖水平，改善营养状况，提高护理满意度。更多还原

【Abstract】 Objective To explore the application effect of individualized enteral nutrition support combined with enhanced recovery after surgery(ERAS) in patients with laryngeal cancer complicated with type 2 diabetes mellitus(T2DM). Methods From October 2022 to October 2024, 102 patients with laryngeal cancer complicated with T2DM who were treated in School of Clinical Oncology in Fujian Medical University(Fujian Provincial Cancer Hospital) were selected. According to different nursing methods, they were divided into control group(routine nursing) and study group(individualized enteral nutrition support combined with ERAS), with 51 cases in each group. The perioperative indicators, blood glucose levels, nutritional status scores and complications were compared between the two groups. Results The nursing satisfaction score of the study group was higher than that of the control group, and the difference was statistically significant(P<0.05). At 3 d, 7 d, 14 d and 1 month after operation, the pain scores of the study group were lower than those of the control group, and the differences were statistically significant(all P<0.05). After nursing, the levels of fasting plasma glucose and 2-hour postprandial plasma glucose in the study group were lower than those in the control group, and the differences were statistically significant(all P<0.05). After nursing, the Subjective Global Nutritional Assessment Form score of the study group was lower than that of the control group, and the difference was statistically significant(P<0.05). There was no significant difference in the incidence of complications between the two groups(P>0.05). Conclusion Patients with laryngeal cancer receiving individualized enteral nutrition support combined with ERAS intervention can reduce postoperative pain, reduce blood glucose levels, improve nutritional status, and improve nursing satisfaction.更多还原